Biochemistry
9th Edition
ISBN: 9781319114671
Author: Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher: W. H. Freeman
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Chapter 32, Problem 15P
Interpretation Introduction
Interpretation:
The examples for the control of gene expression should be given.
Concept introduction:
The gene expression is the phenomenon in which the genetic information encoded in genes is transformed into a functional protein.
Two important processes that control gene expression are transcription and translation. While the former deals with the synthesis of messenger RNA via the action of enzyme RNA polymerase the latter deals with mRNA directed synthesis of protein.
Certain specific regions, for instance, promoter, enhancers, and silencers, known as gene control regions, exist in the genomic DNA which is in transcription.
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Describe two different types of pre-transcriptional control of gene expression? Give an example of each type.
Genetic expression in general can be regulated at various stages. Identify specific processes that control gene expression at the:
a. transcription level -
b. post-transcription level -
c. translation level -
Determine whether the following will increase or decrease gene expression:
mRNA degradation
mRNA capping
Binding of a transcriptional activator
Ubiquitination of a protein and targeting to the proteasome
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- List and discuss four different mechanisms by which vitamins A and D regulate gene expression.arrow_forwardGene expression may change in response to external cues through the activity of multiple signal transduction cascades. What is the primary mechanism that determines if a gene is expressed or not?arrow_forwardDescribe ways to achieve post-transcriptional control of gene expressionarrow_forward
- Choose ONE example of control of gene expression in eukaryotes and describe it in detail. Identify which of the five levels of regulation of gene expression your example represents and explain how your example benefits the cell in which it takes place.arrow_forwardDiscuss factors that might influence the activity of DNA-binding proteins (transcription factors) and bring about changes in gene expression. Include in your answer an example of a process that regulates gene expression at the level of transcriptionarrow_forwardexplain DNA methylation in gene expression Provide examplesarrow_forward
- Choose the statement that correctly characterizes regulated and/or constitutive gene expression. Regulated expression refers to gene expression that is either on or off, depending on the physiological or metabolic status of the cell. Constitutive expression refers to gene expression that is either on or off, depending on the physiological or metabolic status of the cell. Constitutive expression refers to gene expression that is always repressed in response to the absence of required nutrients or other metabolic molecules. Regulated expression refers to gene expression that is always on, regardless of the metabolic or physiological conditions in the cell. Regulated and constitutive expression are terms used to describe gene expression in prokaryotes only.arrow_forwardList the steps in gene expression that are potentiallysubject to regulation.arrow_forwardExplain why protein glycosylation may determine the choice of a protein expression system.arrow_forward
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