Concept explainers
Interpretation:
The reason for the secretion of the enzyme involved in blood clotting as zymogens has to be given.
Concept Introduction:
Blood is a body fluid which flows through the body in the circulatory system.
Blood clot:
- Consists of blood cells trapped in a net of the insoluble fibrous protein known as fibrin.
- It is a multistep process requiring participation of 12 clotting factors.
The formation of blood clot is triggered by two pathways which are intrinsic pathway and extrinsic pathway. Intrinsic pathway starts when blood makes contact with the protein collagen and the extrinsic pathway begins when the damaged tissues releases a membrane glycoprotein known as tissue factor.
Zymogen: Zymogen can be defined as the compound that becomes an active enzyme after a chemical change. Some enzymes can destroy the organ in which they are produced and they are often synthesized as proenzymes or zymogens.
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Fundamentals of General, Organic, and Biological Chemistry (8th Edition)
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