Brock Biology of Microorganisms (15th Edition)
15th Edition
ISBN: 9780134261928
Author: Michael T. Madigan, Kelly S. Bender, Daniel H. Buckley, W. Matthew Sattley, David A. Stahl
Publisher: PEARSON
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Textbook Question
Chapter 27.9, Problem 2MQ
Provide examples and mechanisms for an antibody-mediated autoimmune disease directed against a specific organ and one involving circulating immune complexes.
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Chapter 27 Solutions
Brock Biology of Microorganisms (15th Edition)
Ch. 27.1 - Prob. 1MQCh. 27.1 - Prob. 2MQCh. 27.1 - Distinguish between clonal deletion and clonal...Ch. 27.1 - QWhy is it necessary that all three defining...Ch. 27.2 - Identify the intrinsic and extrinsic properties of...Ch. 27.2 - Describe an epitope recognized by an antibody, and...Ch. 27.2 - Give an example for each: natural and artificial...Ch. 27.2 - QWhat properties are required for a vaccine to...Ch. 27.3 - Summarize antibody production starting with...Ch. 27.3 - Differentiate among antibody classes using...
Ch. 27.3 - Prob. 3MQCh. 27.3 - QDescribe the structural and functional...Ch. 27.4 - Draw a complete Ig molecule and identify...Ch. 27.4 - Describe antigen binding to the CDR1, 2, and 3...Ch. 27.4 - Describe the recombination events that produce a...Ch. 27.4 - QWhich Ig chains are used to construct a complete...Ch. 27.5 - Identify the cells that display MHC class I and...Ch. 27.5 - Compare the MHC I and MHC II protein structures...Ch. 27.5 - Define the sequence of events for processing and...Ch. 27.5 - QDescribe the basic structure of class I and class...Ch. 27.6 - Define polymorphism and polygeny as they apply to...Ch. 27.6 - How does a single MHC protein present many...Ch. 27.6 - QPolymorphism implies that each different MHC...Ch. 27.7 - Prob. 1MQCh. 27.7 - Identify diversity-generating mechanisms unique to...Ch. 27.7 - Describe and compare the structural features of Ig...Ch. 27.7 - QWhat diversity-generating mechanisms function to...Ch. 27.8 - Describe the mechanism used by Tc cells to...Ch. 27.8 - Describe the effector system (the cell-killing...Ch. 27.8 - Compare and contrast the roles and activities of...Ch. 27.8 - QWhat mechanism do Tc cells use to identify and...Ch. 27.9 - Discriminate between immediate hypersensitivity...Ch. 27.9 - Provide examples and mechanisms for an...Ch. 27.9 - QHow do immediate and delayed-type...Ch. 27.10 - Describe the binding site for superantigens on T...Ch. 27.10 - Compare and contrast the immunodeficiency observed...Ch. 27.10 - Prob. 3MQCh. 27.10 - Prob. 1CRCh. 27 - Antibodies of the IgA class are probably more...Ch. 27 - Prob. 2AQCh. 27 - Polymorphism implies that each different MHC...Ch. 27 - What problems would arise if a person had a...
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- Describe 2 distinct mechanisms by which an autoimmune disease can be manifested. Explain exactly what goes awry leading to one's immune system mounting a response to self.arrow_forwardDifferentiate natural vs artificial immunity. Give examples of each.arrow_forward● Differentiate humoral immunity from cellular immunity and the basic roles of B cells and T cells in those systems. Discuss the concept of a clonal immunological response to an epitope. Define antigen presentation and antigen-presenting cell. Describe what makes one antigen more immunogenic than another. Diagram the structures of antibodies and discuss their functions. Explain the differences between primary and secondary antibody responses. Summarize how the immune system generates vast antibody diversity. Describe the role of memory B cells during an antibody response. Explain the two major types of T cells.arrow_forward
- List and explain the four general properties of adaptive immunity.arrow_forwardExplain two pieces of evidence that exist that some self-reactive lymphocytes in the immune system of a normal, healthy organism can be missed and maintain the potential to raise an autoimmune reaction?arrow_forwardExplain the "antigen recognition by cells of adaptive immunity" in a simple way. Relate it with Class I,II,III MHC molecules/genes. Thank you NOTE: Bullet formarrow_forward
- discuss the difference between Antibod Immunity and Cell-mediated immunity.arrow_forwardCite factors involved in autoimmune disease.arrow_forwardDiscuss three differences between antigen and antibodies Explain the structure of the antibody molecule. Discuss the differences between humoral and cell mediated immunity in terms of chemicals and cells involved in each process as they tackle pathogens.arrow_forward
- Complete the table of the Kinds of Immunity by defining each and giving appropriate CLASSIFICATION NATURAL ARTIFICIAL ACTIVE Natural Active - Artificial Active - Examples: Examples: PASSIVE Natural Passive- Artificial Passive- Examples: Examples:arrow_forwardDescribe a type of autoimmune disease. There are many of them. What is an autoimmune disease? Who is susceptible? What is the suggested cause? What is the prognosis for someone with the autoimmune disease that you chose. How is the disease treated?arrow_forwardDefine immunological tolerance, and explain mechanisms that may be responsible for T and B lymphocytes’ tolerance to self-antigens.arrow_forward
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