Explain two pieces of evidence that exist that some self-reactive lymphocytes in the immune system of a normal, healthy organism can be missed and maintain the potential to raise an autoimmune reaction?
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Explain two pieces of evidence that exist that some self-reactive lymphocytes in the immune system of a normal, healthy organism can be missed and maintain the potential to raise an autoimmune reaction?
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- Nowadays, in the clinical field of cancer vaccines, is there a potential to eliciting autoimmune destruction?A 40-year-old man with a complement deficiency agrees to participate in a clinical study of immune mechanisms. The subject is unable to activate the complement system by the classical pathway, but he can activate the complement system by the alternate pathway. Deletion of which of the following components is consistent with these findings? A) C2 B) C3 C) C5 D) C8 E) Factor B F) Factor D OG) Factor H OH) von Willebrand factorThe transplantation of organs from one person to another was impossible until the discovery of immunosuppressive drugs. Now, with the use of drugs such as cyclosporine, organs can be transplanted without rejection. Transplant patients must take immunosuppressive drugs for the remainder of their lives. What are the potential risks associated with long-term use of immunosuppressive drugs?
- Many cells in the human body have proteins on the surface that are able to interact with the receptors of helper T cells. Explain the mechanisms and why it is that such an interaction or signal does not usually result in an autoimmune reaction?discuss the difference between Antibod Immunity and Cell-mediated immunity.Describe the specific roles of helper, regulatory, and cytotoxic T cells in normal cellular immunity.
- .A table comparing the biological characteristics of the five classes of immunoglobulins is shown below. Answer yes or no in the spaces provided, (You can draw the table in your answer paper) IgE IgD Biological activity a) Activates classical complement pathway b) Present on the membrane of the mature B cells c) Present in secretions d) Induces mast-cell degranulation e) Crosses placenta IgG IgA IgMInnate lymphoid cells reside primarily in tissues such as the lungs, the lining of the gastrointestinal tract, and the skin, because these sites represent the major routes of entry of pathogens into the body. Several different subsets of innate lymphoid cells exist, and each is specialized to respond to a category of pathogen (e.g., viruses, extracellular bacteria, helminthic parasites, etc). a) True b) FalseExplain what is meant by serotype-specific immunity.