Human Physiology: An Integrated Approach (8th Edition)
Human Physiology: An Integrated Approach (8th Edition)
8th Edition
ISBN: 9780134605197
Author: Dee Unglaub Silverthorn
Publisher: PEARSON
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Chapter 26.4, Problem 18CC
Summary Introduction

To determine: The effect of administration of aromatase inhibitor on the ovarian cycle of women.

Introduction: Menstrual cycle is a series of events in which hormonal changes take place in females’ ovary and uterine wall. The menstrual cycle is formed from the combination of two different cycles, ovarian cycle, and uterine cycle. The uterine cycle is divided into three different phases, which are menstruation, proliferative, and secretory phase. Estrogen is important for the proliferative phase because it induces mitosis in the basal layer as well as it allows the re-growth of blood vessels.

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Clomiphene Citrate is a fertility drug that stimulates hypothalamic secretion of Gonadotropin releasing Hormone (GnRH) in females and induces ovulation. Explain how increased GnRH with Clomiphene Citrate treatment would affect follicle maturation and ovulation in women (explain how increased GnRH would affect FSH, LH, Estrogen, and ovulation).
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Human Physiology: An Integrated Approach (8th Edition)

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