Explanation Given information: A life-threatening condition is congenital adrenal hyperplasia. It results from due to the deficiency in the P 450 enzyme steroid 21-hydroxylase. This enzyme usually catalyzes the initial step involved in the conversion of progesterone into aldosterone and cortisol. Congenital adrenal hyperplasia can be explained as several autosomal recessive diseases. These diseases occur due to the mutations. These mutations take place in genes of the enzymes that regulate the biosynthetic steps of the steroidogenesis...

9th Edition

ISBN: 9781319114671

Author: Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher: W. H. Freeman

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Question

Chapter 26, Problem 33P

Interpretation Introduction

Interpretation:

The reason for a rise in sex hormone production during the congenital adrenal hyperplasia should be determined.

Concept introduction:

Enzymes that are produced from the cytochrome P₄₅₀ genes usually facilitates the synthesis and metabolism of several chemicals and molecules within cells. Common variations in the cytochrome P₄₅₀ genes can influence the role of the enzymes.

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Chapter 26, Problem 32P

Chapter 26, Problem 34P

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Chapter 26 Solutions

Biochemistry

Ch. 26 - Prob. 1P Ch. 26 - Prob. 2P Ch. 26 - Prob. 3P Ch. 26 - Prob. 4P Ch. 26 - Prob. 5P Ch. 26 - Prob. 6P Ch. 26 - Prob. 7P Ch. 26 - Prob. 8P Ch. 26 - Prob. 9P Ch. 26 - Prob. 10P

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