Concepts of Genetics (12th Edition)
12th Edition
ISBN: 9780134604718
Author: William S. Klug, Michael R. Cummings, Charlotte A. Spencer, Michael A. Palladino, Darrell Killian
Publisher: PEARSON
expand_more
expand_more
format_list_bulleted
Concept explainers
Videos
Textbook Question
Chapter 26, Problem 2NST
Determine whether the following two sets of data represent populations that are in Hardy-Weinberg equilibrium.
- (a) CCR5 genocypes: 1/1, 60 percent; 1/Δ32, 35.1 percent; Δ32/Δ32, 4.9 percent
- (b) Sickle-cell hemoglobin: SS, 75.6 percent; Ss, 24.2 percent; ss, 0.2 percent (S = normal hemoglobin allele; s = mutant hemoglobin allele)
Expert Solution & Answer
Want to see the full answer?
Check out a sample textbook solution
Students have asked these similar questions
Solve the given hardy-Weinberg principle. A population has a total number of 5222 and with ?^?=0.32 (A=normal hemoglobin; a=with sickle-cell anemia). Answer the following questions
The following frequencies were gathered in an African population affected with sickle-cell anemia: SS, 75.5%; Ss, 23.0%; ss, 1.5% (S = normal hemoglobin allele; s = mutant hemoglobin allele). Calculate the genotypic frequencies and determine whether this data represent a population that is in HWE.
A study on blood types in a population found the following genotypic distribution among the people sampled: 1101 were MM, 1496 were MN and 503 were NN.
i) calculate the allelic genotypic frequencies.
ii) using x² test, determine whether or not this population is in Hardy-Weinberg equilibrium. Important information from the x² distribution is given in the picture attached.
Chapter 26 Solutions
Concepts of Genetics (12th Edition)
Ch. 26 - The ability to taste the compound...Ch. 26 - Determine whether the following two sets of data...Ch. 26 - If the albino phenotype occurs in 1/10,000...Ch. 26 - A prospective groom, who is unaffected, has a...Ch. 26 - In a region of Quebec, Canada, 1 in 22 people are...Ch. 26 - Critics argue that a uniform panel of disorders...Ch. 26 - Others argue that the current testing system...Ch. 26 - HOW DO WE KNOW? Population geneticists study...Ch. 26 - CONCEPT QUESTION Read the Chapter Concepts list on...Ch. 26 - Price et al. [(1999).J. Bacteriol181:2358-2362)...
Ch. 26 - The genetic difference between two Drosophila...Ch. 26 - The use of nucleotide sequence data to measure...Ch. 26 - Prob. 6PDQCh. 26 - What must be assumed in order to validate the...Ch. 26 - In a population where only the total number of...Ch. 26 - If 4 percent of a population in equilibrium...Ch. 26 - Consider a population in which the frequency of...Ch. 26 - If the initial allele frequencies are p = 0.5 and...Ch. 26 - Under what circumstances might a lethal dominant...Ch. 26 - Assume that a recessive autosomal disorder occurs...Ch. 26 - One of the first Mendelian traits identified in...Ch. 26 - Describe how populations with substantial genetic...Ch. 26 - Achondroplasia is a dominant trait that causes a...Ch. 26 - Prob. 17PDQCh. 26 - Prob. 18PDQCh. 26 - A botanist studying water lilies in an isolated...Ch. 26 - A farmer plants transgenic Bt corn that is...Ch. 26 - In an isolated population of 50 desert bighorn...Ch. 26 - To increase genetic diversity in the bighorn sheep...Ch. 26 - What genetic changes take place during speciation?Ch. 26 - Some critics have warned that the use of gene...Ch. 26 - Prob. 25PDQCh. 26 - What are the two groups of reproductive isolating...Ch. 26 - A form of dwarfism known as Ellisvan Creveld...Ch. 26 - The original source of new alleles, upon which...Ch. 26 - A number of comparisons of nucleotide sequences...Ch. 26 - Shown below are two homologous lengths of the...Ch. 26 - Recent reconstructions of evolutionary history are...
Additional Science Textbook Solutions
Find more solutions based on key concepts
Problem Set
True or False? Indicate whether each of the following statements about membrane transport is true (...
Becker's World of the Cell (9th Edition)
More than one choice may apply. Using the terms listed below, fill in the blank with the proper term. anterior ...
Essentials of Human Anatomy & Physiology (12th Edition)
Propose a model for the assembly of a flagellum in a typical Gram-positive cell envelope.
Prescott's Microbiology
Describe the evolution of mammals, tracing their synapsid lineage from early amniote ancestors to true mammals....
LooseLeaf for Integrated Principles of Zoology
What are the cervical and lumbar enlargements?
Principles of Anatomy and Physiology
Why is it unlikely that two neighboring water molecules would be arranged like this?
Campbell Biology (11th Edition)
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- Determine whether the following two sets of datarepresent populations that are in Hardy–Weinbergequilibrium. Sickle-cell hemoglobin: SS, 75.6 percent; Ss, 24.2 percent;ss, 0.2 percent (S = normal hemoglobin allele; s =mutant hemoglobin allele)arrow_forwardTable 1. Use the numbers of individuals with each of the three CCRS genotypes among 1318 Caucasian blood donors, to fill in the empty boxes (Data Source: Glass et al. 2006) Numbers observed Frequency observed (round to 3 decimal places) Frequency expected for population in HWE (round to 3 decimal places) +/+ Numbers of individuals expected (frequency expected times 1318, round to nearest whole number) 1102 Genotypes +/A32 Use the data above to calculate allele frequencies. Freq of + Freq of 432 203 432/432 13 (round to 3 decimal places) row must sum to -1 values must sum to-1 row must sum to-1 row sums to 13187arrow_forwardThe above data are from a landmark student looking into the relationship between sickle cell anemia and malaria. These data are from a population where malaria is prevalent. A is the allele for normal red blood cells; S is the sickle cell allele (you should know what this means). Is this population in H-W equilibrium? Make sure to use chi-square. Why or why not (if not, what assumption(s) violated). Genotype AA AS SS Total Observed 9365 (75.6%) 2993 (24.2%) 29 (0.2%) 12,387arrow_forward
- While studying the frequency of sickle-cell disease ("sickle cell anemia") in a population living in sub-Saharan Africa, you obtain the following data from a sample of n= 100 people (note that I chose a simpler system for identifying the alleles rather than using "Hb S" for sickle cell allele), which is the actual name and what you used in lab). What is the frequency of the sickle cell allele (b) in the sample below from a human population? Sample Data BB-60 individuals (No sickle cell disease) Bb-30 individuals (No sickle cell disease) bb-10 individuals (Sickle cell disease) 1. 0.25 2. 0.10 3. 0.35 4. 0.60 5. 0.20arrow_forward8% of XY individuals are color blind in a population. Assume Hardy-Weinberg conditions. Submit your answer as it is. a) What is the percentage of color-blind XX individuals? b) What is the percentage of XX individuals who are carriers? c) If this population has 1000 individuals with 50% of male and 50% of female, how many carriers are present in this population? Submit your answer as it is. Do not round up.arrow_forwardNote there are no cells on this panel that have a double dose (homozygous) of the K antigen. Which of the following statements is true regarding the K+k- phenotype? Question 6 options: A) The phenotype is rare due to the high prevalence of the k antigen in the population. B) The phenotype is uncommon but does occur in about 10% of the population. C) The phenotype occurs in about 50% of the population. D) Although the phenotype is not represented on this antibody panel, it is fairly common in the population.arrow_forward
- Phenylketonuria is a recessive autosomal genetic disorder that can cause mental retardation. Phenylketonuria is particularly common in Turkey, where 1 in 2600 children are born with the disease. As of 2011, the population of Turkey was 73.6 million. Based on this data, and assuming that the Turkish population is in Hardy-Weinberg equilibrium. (a) Estimate the number of carriers of phenylketonuria in Turkey (b) Estimate the proportion of unaffected individuals who are carriers.arrow_forwardThe hemoglobin B gene (Hb) has a common allele (A) ofa SNP (rs334) that encodes the HbA form of (adult) hemoglobin and a rare allele (T ) that encodes the sicklingform of hemoglobin, HbS. Among 571 residents of a village in Nigeria, 440 were A/A and 129 were A/T, and 2were T/T individuals were observed. Use the χ2 test todetermine whether these observed genotypic frequencies fit Hardy–Weinberg expectations.arrow_forward(1 point) Humans with the genotypes DD and Dd show the Rh+ blood phenotype, whereas those with the genotype dd show the Rh- blood phenotype. In a sample of 400 Basques from Spain, 230 people were Rh+ and 170 people were Rh-. Assuming that this population is in Hardy-Weinberg proportions, what is the allele frequency of the allele D? (a) (a) 0.348 (answer) (b) (b) 0.652 (c) (c) 0.425 (d) (d) 0.575 (e) (e) 0.288 2. (2 points) In the Basque population mentioned above, what proportion of the Rh+ individuals would be expected to be heterozygote? (a) (a) 0.454 (b) (b) 0.789 (answer) (c) (c) 0.516 (d) (d) 0.250 (e) (e) 0.500 How is the answer for #2, b? please explainarrow_forward
- Compare the 95% confidence interval for the difference between two true means with the 95% confidence interval for an individual true kean. Describe one way in which these two equations are similar and state four ways in which these equations differ.arrow_forwardWhat is the first variable that can be calculated given these data, and what is the final variable we are requesting you to calculate? "In Finland, 256 people out of 10,000 are homozygous for the CCR5 allele mutation resulting in HIV resistance. Assuming the locus is in Hardy-Weinberg equilibrium, what is the expected genotype frequency of heterozygous carriers for the CCR5 mutation?"arrow_forwardIn humans, people with at least one dominant RhD allele have a Rh positive blood type. People with a homozygous recessive genotype have a Rh negative blood type. In the United States, 85% of the population is Rh positive and 15% are Rh negative. What are the values of p and q for the population in the United States (assuming that the American population is at Hardy-Weinberg equilibrium)?arrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
Human Heredity: Principles and Issues (MindTap Co...BiologyISBN:9781305251052Author:Michael CummingsPublisher:Cengage Learning
Human Heredity: Principles and Issues (MindTap Co...
Biology
ISBN:9781305251052
Author:Michael Cummings
Publisher:Cengage Learning
What is Evolution?; Author: Stated Clearly;https://www.youtube.com/watch?v=GhHOjC4oxh8;License: Standard Youtube License