Concept explainers
(a)
Interpretation: To determine whether glutamate and aspartate could function as the two reactants in a transamination reaction or not.
Concept introduction: Transamination reaction is a biochemical reaction that involves the transfer of an amino group. In transamination reaction exchange of an amino group from an
The general structure of an amino acid is:
Here,
An acid containing both carbonyl and carboxyl
(a)
Answer to Problem 26.34EP
No, glutamate and aspartate cannot function as the reactants in a transamination reaction.
Explanation of Solution
Glutamate is an amino acid and its structure is:
Aspartate is an amino acid and its structure is:
The two reactants in transamination reaction are a keto acid and an amino acid. Both glutamate and aspartate are amino acids thus they cannot function as reactants in a transamination reaction. For a transamination reaction to take place there must be one amino acid present along with a keto acid.
(b)
Interpretation: To determine whether aspartate and
Concept introduction: Transamination reaction is a biochemical reaction that involves the transfer of an amino group. In transamination reaction exchange of an amino group from an
The general structure of an amino acid is:
Here,
An acid containing both carbonyl and carboxyl functional group is known as a keto acid. A general representation of a keto acid is:
(b)
Answer to Problem 26.34EP
Yes, aspartate and
Explanation of Solution
Aspartate is an amino acid and its structure is:
Transamination reaction involves the exchange of an amino group from an
(c)
Interpretation: To determine whether succinate and
Concept introduction: Transamination reaction is a biochemical reaction that involves the transfer of an amino group. In transamination reaction exchange of an amino group from an
The general structure of an amino acid is:
Here,
An acid containing both carbonyl and carboxyl functional group is known as a keto acid. A general representation of a keto acid is:
(c)
Answer to Problem 26.34EP
No, succinate and
Explanation of Solution
Succinate is a diacid acid and its structure is:
The two reactants in transamination reaction are a keto acid and an amino acid.
(d)
Interpretation: To determine whether glutarate and aspartate could function as the two reactants in a transamination reaction or not.
Concept introduction: Transamination reaction is a biochemical reaction that involves the transfer of an amino group. In transamination reaction exchange of an amino group from an
The general reaction to illustrate transamination is as follows:
The general structure of an amino acid is:
Here,
An acid containing both carbonyl and carboxyl functional group is known as a keto acid. A general representation of a keto acid is:
(d)
Answer to Problem 26.34EP
No, glutarate and aspartate cannot function as the reactants in a transamination reaction.
Explanation of Solution
Aspartate is an amino acid and its structure is:
Glutarate is a diacid and its structure is:
The two reactants in transamination reaction are a keto acid and an amino acid. Aspartate is an amino acid but glutarate is not a keto acid. For a transamination reaction to take place there must be one keto acid present along with an amino acid. Thus, glutarate and aspartate cannot function as the reactants in a transamination reaction.
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Chapter 26 Solutions
EBK GENERAL, ORGANIC, AND BIOLOGICAL CH
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- Five coenzymes are required by a-ketoglutarate dehydrogenase, the enzyme in the citric acid cycle that converts a-ketoglutarate to succinyl-CoA.a. Identify the coenzymes.b. Propose a mechanism for the reaction. A-ketoglutarate dehydrogenase A-ketoglutarate succinyl-CoAOO OO O−O O− −O SCoA + CO2arrow_forwardN-Acetylglutamate is required as a cofactor in the synthesis of carbamoyl phosphate. How is N-acetylglutamate synthesized from glutamate?arrow_forwardN -Acetylglutamate is required as a cofactor in the synthesis of carbamoyl phosphate. How is Nacetylglutamate synthesized from glutamate?arrow_forward
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