Fundamentals of Biochemistry: Life at the Molecular Level
Fundamentals of Biochemistry: Life at the Molecular Level
5th Edition
ISBN: 9781118918401
Author: Donald Voet, Judith G. Voet, Charlotte W. Pratt
Publisher: WILEY
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Chapter 25, Problem 42CQ
Summary Introduction

To determine: Whether the Chi sequences occur at a random rate and how much more or less frequently do they occur than random.

Concept introduction: E. coli chromosome consists of one circular chromosomal DNA which has 4639 kb of genomic information. Its chromosome contains many genes that regulate cellular metabolic activities. Chi sequence is a short sequence present at the site where the homologous recombination occurs. It consists of 8 nucleotide segments GCTGGTGG which provide a signal for RecBCD enzyme.

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