Concept explainers
To determine: The base to which the modified cytosine pairs.
Concept introduction: A base analogue is a chemical that has a similar structure of either a purine or a pyrimidine. Hydroxylamine (NH2OH) is an inorganic chemical that is capable of inducing transition mutation in the DNA structure. One such mutagenic effect converts cytosine to a modified cytosine, which pairs with adenine rather than pairing with guanine. This is an example for transition mutation.
To explain: Whether a modified cytosine base-pair addition generates transition or transversion mutation.
Concept introduction: A base analogue is a chemical which has a similar structure to that of either a purine or a pyrimidine. Hydroxylamine (NH2OH) is an inorganic chemical that is capable of inducing transition mutation in the DNA structure. One such mutagenic effect converts the cytosine to a modified cytosine, which pair with adenine rather than pairing with guanine. This is an example for transition mutation.
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