Brock Biology of Microorganisms (15th Edition)
15th Edition
ISBN: 9780134261928
Author: Michael T. Madigan, Kelly S. Bender, Daniel H. Buckley, W. Matthew Sattley, David A. Stahl
Publisher: PEARSON
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Textbook Question
Chapter 25, Problem 2AQ
Although mutants incapable of producing exotoxins are relatively easy to isolate, mutants incapable of producing endotoxins are much harder to isolate. From what you know of the structure and function of these types of toxins, explain the differences in mutant recovery.
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Chapter 25 Solutions
Brock Biology of Microorganisms (15th Edition)
Ch. 25.1 - What event is required but not sufficient to cause...Ch. 25.1 - Prob. 2MQCh. 25.1 - Prob. 1CRCh. 25.2 - Prob. 1MQCh. 25.2 - Prob. 2MQCh. 25.2 - Prob. 3MQCh. 25.2 - Prob. 1CRCh. 25.3 - What are virulence factors? How can the LD50 test...Ch. 25.3 - Prob. 2MQCh. 25.3 - Prob. 1CR
Ch. 25.4 - Prob. 1MQCh. 25.4 - Prob. 2MQCh. 25.4 - Prob. 3MQCh. 25.4 - Prob. 1CRCh. 25.5 - Prob. 1MQCh. 25.5 - Prob. 2MQCh. 25.5 - Prob. 3MQCh. 25.5 - Prob. 1CRCh. 25.6 - What key features are shared by all AB exotoxins?Ch. 25.6 - Prob. 2MQCh. 25.6 - Prob. 3MQCh. 25.6 - Prob. 1CRCh. 25.7 - Prob. 1MQCh. 25.7 - Prob. 2MQCh. 25.7 - QDistinguish between the mechanism of cytotoxins...Ch. 25.8 - What part of the Escherichia coli cell contains...Ch. 25.8 - Why is it necessary to test for endotoxin in water...Ch. 25.8 - Prob. 1CRCh. 25 - Coagulase is a virulence factor for Staphylococcus...Ch. 25 - Although mutants incapable of producing exotoxins...
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- (b) List TWO (2) types of common food hazards. Describe the properties of bacteria endotoxin based on the following component; (i) (ii) (iii) Stability Antigenicity Toxicityarrow_forwardWhich of the following is NOT true of bacterial exotoxins? 1. Important in the pathogenesis of many human diseases 2. Their toxic effect can be systemic, affecting cells distant from the primary site of infection 3. None of the other four answers (All are true of bacterial exotoxins) 4. Different exotoxins may affect different types of cells (e.g., nerves, gastrointestinal mucosa) 5. Some exotoxins have two components, A (active) and B (binding)arrow_forwardChoose one infectious disease from the list below and use the chain of infection to analyze how it is spread. A. Please provide a comprehensive description of cholera. B. Describe the chain of infection cholera. The chain of infection for the chosen infectious disease must clearly include the following: 1. Identification of a) the pathogen, b) the reservoir c) means of transmission d) the susceptible host 2. Describe how one could break the chain of cholera, such as breaking the pathogen link, by providing a specific intervention. 3. Include references and relevant data.arrow_forward
- Here are four toxins: diphtheria toxin, cholera toxin, tetanus toxin, and exfoliative toxin. Choose two of them and answer the following questions: 1. Is it an exotoxin or an endotoxin? 2. Which bacterial species produces it? 3. Briefly describe its mode of action and how it causes damage to the host cells. Include specific signs and symptoms.arrow_forwardCompare and contrast the exotoxins and endotoxin. What are the limitations in their detection by molecular methods?arrow_forwardDifferent strains of Streptococcus pyogenes have different virulence factors, giving these microbes much versatility. Virulence factors include which of the following? Choose one or more: A.A capsule that, when thick, will help the organism avoid phagocytosis by macrophages B.A cell wall containing lipoteichoic acid, thought to facilitate adherence to pharyngeal epithelial cells C.Enzymes that lyse blood cells (streptolysins) D.The production of several endotoxins called streptococcal pyogenic endotoxins (SPEs)arrow_forward
- Compare and contrast Bacterial Endotoxins and Exotoxins at 4 levels:arrow_forwardAll of the following statements concerning endotoxins are correct except: Select one: A. they are produced only by Gram (+) cells B. they consist primarily of lipopolysaccharides C. they have systemic, rather than targeted, effects of the host D. they must be present in relatively high doses to effect the host E. they are released from a pathogen when it is dead or dyingarrow_forwardPathogens have a variety of traits that interact with a host and enable the pathogen to enter a host, adhere to host cells, gain access to nutrients, and escape detection or removal by the immune system. These traits are called virulence factors. The following enzymes and toxin can act as virulence factors and contribute to bacteria’s pathogenicity. What are the specific actions of the following enzymes and toxin that make them virulence factors? Coagulase Kinase (such as staphylokinases and streptokinases) Hyaluronidase Collagenase Cytotoxinarrow_forward
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