Organic Chemistry (6th Edition)
6th Edition
ISBN: 9781260119107
Author: Janice Gorzynski Smith
Publisher: McGraw Hill Education
expand_more
expand_more
format_list_bulleted
Question
Chapter 23.6, Problem 8P
Interpretation Introduction
Interpretation: Among the given
Concept Introduction: Gabriel synthesis is a method of preparation of primary amines. This is a nucleophilic substitution reaction. The phthalimide in presence of base forms the resonance stabilized anion which acts as a nucleophile and attacks the electrophilic carbon of alkyl haides.
Expert Solution & Answer
Want to see the full answer?
Check out a sample textbook solution
Students have asked these similar questions
Which amines cannot be prepared by a Gabriel synthesis? Explain your choices.
NH2
NH2
NH2
а.
b.
C.
d.
Which amines cannot be prepared by the Gabriel synthesis? Explain your choices.
Answer the following questions about atomoxetine, a drug used to treatattention deficit hyperactivity disorder (ADHD).
a.) What amides can be reduced to form atomoxetine?b.) What starting materials can be used to form atomoxetine by reductiveamination? Draw all possible methods.c.) What products are formed by Hofmann elimination of atomoxetine?
Chapter 23 Solutions
Organic Chemistry (6th Edition)
Ch. 23.2 - Prob. 1PCh. 23.3 - Prob. 2PCh. 23.3 - Prob. 3PCh. 23.4 - Prob. 4PCh. 23.6 - Prob. 7PCh. 23.6 - Prob. 8PCh. 23.6 - Prob. 9PCh. 23.6 - Prob. 10PCh. 23.6 - Prob. 11PCh. 23.6 - Prob. 12P
Ch. 23.6 - Prob. 13PCh. 23.6 - Prob. 14PCh. 23.6 - Prob. 15PCh. 23.8 - Prob. 16PCh. 23.8 - Problem 25.18
Write out steps to show how each of...Ch. 23.9 - Prob. 18PCh. 23.9 - Prob. 19PCh. 23.9 - Prob. 20PCh. 23.9 - Problem 25.22
Which nitrogen atom in each compound...Ch. 23.9 - Prob. 22PCh. 23.10 - Prob. 23PCh. 23.10 - Prob. 24PCh. 23.11 - Prob. 25PCh. 23.11 - Prob. 26PCh. 23.11 - Problem 25.28
Draw the major product formed in...Ch. 23.12 - Prob. 28PCh. 23.13 - Prob. 29PCh. 23 - Give a systematic or common name for each...Ch. 23 - Prob. 38PCh. 23 - 25.40 How many stereogenic centers are present in...Ch. 23 - 25.41 Rank the compounds in each group in order of...Ch. 23 - 25.42 Decide which atom in each molecule is most...Ch. 23 - Prob. 47PCh. 23 - Prob. 48PCh. 23 - Prob. 49PCh. 23 - 25.52 Draw the products formed when methylaniline ...Ch. 23 - Prob. 53PCh. 23 - 25.60 A chiral amine A having the configuration...Ch. 23 - Prob. 68PCh. 23 - Prob. 69PCh. 23 - Prob. 70PCh. 23 - 25.70 Devise a synthesis of each biologically...Ch. 23 - 25.71 Devise a synthesis of each compound from...
Knowledge Booster
Similar questions
- Amines can be protected by different protecting groups as indicated below. Which of the following is stable to an acid or a base in water. А. В. С. D.arrow_forwarda. b. 22.16 Using ammonia as your source of nitrogen, show the reagents you would use to prepare each of the following amines: C. d. e. O f. PRACTICE the skill H Answer xi -N -NH₂ H O 1) [H*] NaBH₂CN NH3 2) [H*] NaBH3CN CH3CHOarrow_forwardComplete the flowchart by drawing the resulting structures of each reaction. A. B. C. D. E. F. G. H. I.arrow_forward
- 2. How many different ß-hydroxyaldehydes and ß-hydroxyketones, including constitutional isomers and stereoisomers, are formed upon treatment of a mixture of acetone and benzaldehyde with base? a. b. 2 c. 3 d. 4arrow_forward17. Rank the acid derivatives with respect to their reactivity with water. acid halide > ester > acid anhydride > amide acid anhydride > amide > acid halide > ester amide > ester > acid anhydride > acid halide acid halide > acid anhydride > ester > amide A) B) C) D) 18. Disregarding A) 3 stereoisomers, how many different enols can the B-diketone CH3COCH₂COCH₂CH3 form? B) 1 C) 4 D) O E) 2arrow_forwardamine reaction in bumetamide, not using an acid or basearrow_forward
- What amide(s) can be used to prepare each amine by reduction?arrow_forward2）Rank the following in order of basicity and explain your choices.arrow_forwardTest for Amines a. Hinsberg test: General Reaction Reagents: Positive result: Notes: b. Nitrous acid test: General Reaction Reagents: Positive result: Notes:arrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
Organic Chemistry: A Guided InquiryChemistryISBN:9780618974122Author:Andrei StraumanisPublisher:Cengage Learning
Organic Chemistry: A Guided Inquiry
Chemistry
ISBN:9780618974122
Author:Andrei Straumanis
Publisher:Cengage Learning