Becker's World of the Cell (9th Edition)
Becker's World of the Cell (9th Edition)
9th Edition
ISBN: 9780321934925
Author: Jeff Hardin, Gregory Paul Bertoni
Publisher: PEARSON
bartleby

Videos

Textbook Question
Book Icon
Chapter 23, Problem 23.1CC

One effect of the hormone insulin is to cause liver cells to make glycogen. Assume the dissociation constant (Kd) for the interaction of insulin with its receptor is 10−7 M. A hypoglycemic patient’s insulin receptors have a Kd of 10−8. Why would such a patient have low blood sugar?

Expert Solution & Answer
Check Mark
Summary Introduction

To determine: The criteria of low blood sugar level of a patient.

Introduction: The sugar level is the concentration of glucose level of the blood. Levels of the glucose are manipulated by the functioning of the pancreas. The pancreas regulates the glucose levels in the blood by the effect of insulin hormone.

Explanation of Solution

In the liver cells, the capacity of the proteins (insulin hormone) to bind the liver cell receptors is inversely proportional to the Kd. The smaller Kd in the patients represents strong binding with the liver receptor cells. This results in the high activity of the binding in the patients than the normal persons.

At a certain period of time, a person with smaller Kd shows the high interaction of insulin binding to the receptors. The rate of binding of the insulin molecules to the receptor cells emits the signal for the glucose entry to the cells. This event decreases the amount of glucose in the bloodstream of the person. Hence, Kd plays an important role in the regulation of blood sugar level of an individual.

Thus, the patient with Kd of 10-8 has low sugar level than the patient with Kd of10-7.

Want to see more full solutions like this?

Subscribe now to access step-by-step solutions to millions of textbook problems written by subject matter experts!
Students have asked these similar questions
Bodybuilders use a variety of anabolic substances to gain mass. Two such compounds are insulin and trenbolone. Insulin has significant anabolic and anti-catabolic properties and impacts the metabolism of various macromolecules, not just that of carbohydrates. Trenbolone binds the androgen receptor with an affinity five times higher than that of testosterone and is popular for its fat-burning and anabolic properties. H. Trenbolone C18H2202 Insulin C257H383NosO77S6 How do the different targets, mechanisms of action and durations of each drug ultimately lead to the same desired effect (increase in lean body mass)?
Write a balanced equation for the hydrolysis of cGMP, catalyzed by cGMP phosphodiesterase. Would you expect an inhibitor of this enzyme to potentiate or antagonize the action of Viagra? Explain.
A female neonate did well until approximately 24 hours of age when she became lethargic. A sepsis workup proved negative. At 56 hours, she started showing focal seizure activity. The plasma ammonia level was found to be 1,100 μmol/L (normal 5–35 μmol/L). Quantitative plasma amino acid levels revealed a marked elevation of argininosuccinate.19.3   Which one of the following enzymic activities is most likely to be deficient in this patient? EXPLAIN your answerA. Arginase.B. Argininosuccinate lyase.C. Argininosuccinate synthase.D. Carbamoyl phosphate synthetase I.E. Ornithine transcarbamoylase.
Knowledge Booster
Background pattern image
Biology
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.
Similar questions
SEE MORE QUESTIONS
Recommended textbooks for you
Text book image
Human Anatomy & Physiology (11th Edition)
Biology
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:PEARSON
Text book image
Biology 2e
Biology
ISBN:9781947172517
Author:Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:OpenStax
Text book image
Anatomy & Physiology
Biology
ISBN:9781259398629
Author:McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa Stouter
Publisher:Mcgraw Hill Education,
Text book image
Molecular Biology of the Cell (Sixth Edition)
Biology
ISBN:9780815344322
Author:Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter
Publisher:W. W. Norton & Company
Text book image
Laboratory Manual For Human Anatomy & Physiology
Biology
ISBN:9781260159363
Author:Martin, Terry R., Prentice-craver, Cynthia
Publisher:McGraw-Hill Publishing Co.
Text book image
Inquiry Into Life (16th Edition)
Biology
ISBN:9781260231700
Author:Sylvia S. Mader, Michael Windelspecht
Publisher:McGraw Hill Education
What is a Primary and Secondary Metabolite?; Author: Unicity International;https://www.youtube.com/watch?v=TRNUURm0agM;License: Standard Youtube License