Concepts of Genetics (12th Edition)
12th Edition
ISBN: 9780134604718
Author: William S. Klug, Michael R. Cummings, Charlotte A. Spencer, Michael A. Palladino, Darrell Killian
Publisher: PEARSON
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Textbook Question
Chapter 23, Problem 19ESP
The apterous gene in Drosophila encodes a protein required for wing patterning and growth. It is also known to function in nerve development, fertility, and viability. When human and mouse genes whose protein products closely resemble apterous were used to generate transgenic Drosophila [Rincon-Limas et al. (1999). Proc. Nat. Acad. Sci. (USA) 96:2165–2170], the apterous mutant
- (a) What is meant by the term rescued in this context?
- (b) What do these results indicate about the molecular nature of development?
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Chapter 23 Solutions
Concepts of Genetics (12th Edition)
Ch. 23 - Suppose you initiate a screen for maternal-effect...Ch. 23 - Prob. 2NSTCh. 23 - Prob. 1CSCh. 23 - Prob. 2CSCh. 23 - Prob. 1PDQCh. 23 - Prob. 2PDQCh. 23 - Prob. 3PDQCh. 23 - Nuclei from almost any source may be injected into...Ch. 23 - Distinguish between the syncytial blastoderm stage...Ch. 23 - Prob. 6PDQ
Ch. 23 - Prob. 7PDQCh. 23 - List the main classes of zygotic genes. What is...Ch. 23 - Experiments have shown that any nuclei placed in...Ch. 23 - Prob. 10PDQCh. 23 - Prob. 11PDQCh. 23 - Prob. 12PDQCh. 23 - Prob. 13PDQCh. 23 - Prob. 14PDQCh. 23 - Prob. 15PDQCh. 23 - Prob. 16PDQCh. 23 - Prob. 17PDQCh. 23 - A number of genes that control expression of Hox...Ch. 23 - The apterous gene in Drosophila encodes a protein...Ch. 23 - In Arabidopsis, flower development is controlled...Ch. 23 - Prob. 21ESPCh. 23 - Prob. 22ESPCh. 23 - Much of what we know about gene interactions in...Ch. 23 - Dominguez et al. (2004) suggest that by studying...
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- The restriction digests of the cloned Drosophila gene can provide direct visible evidence of a mutation, as these samples come from a clone of the gene. In order to similarly detect a mutation in the copy of the endogenous gene within the Drosophila genome, a mechanism for specifically detecting restriction fragments from that gene among the complex set of fragments generated in a restriction digest of the entire Drosophila genome. Remember that the Drosophila melanogaster genome consists of ~123,000 kb. For a 10.2 kb Drosophila gene, what fraction of the genome does this gene constitute?arrow_forwardChristiane Nüsslein-Volhard and her colleagues carried out several experiments in an attempt to understand what determines the anterior and posterior ends of a Drosophila larva (reviewed in C. NüssleinVolhard, H. G. Frohnhofer, and R. Lehmann. 1987. Science 238:1675– 1681). They isolated fruit flies with mutations in the bicoid gene (bcd−). These flies produced embryos that lacked a head and thorax. When they transplanted cytoplasm from the anterior end of an egg from a wild-type female into the anterior end of an egg from a mutant bicoid female, normal head and thorax development took place in the embryo. However, transplanting cytoplasm from the posterior end of an egg from a wild-type female into the anterior end of an egg from a bicoid femalehad no effect. Explain these results in regard to what you know about proteins that control the determination of the anterior–posterior axis.arrow_forwardCap, EA1, and Sap are all genes/proteins of interest in this study. For each gene, what gene product is encoded and where is the gene (the literal DNA sequence) located physically in the cell? I need help fimiding this in the artticle and answer as short as possible https://www.ncbi.nlm.nih.gov/pmc/articles/PMC106848/arrow_forward
- Our understanding of maternal effect genes has been greatly aided by their identification in experimental organisms such as Drosophila melanogaster and Caenorhabditis elegans. In experimental organisms with a short generation time, geneticists have successfully searched for mutant alleles that prevent the normal process of embryonic development. In many cases, the offspring die at early embryonic or larval stages. These are called maternal effect lethal alleles. How would a researcher identify a mutation that produced a recessive maternal effect lethal allele?arrow_forwardChristiane Nüsslein-Volhard and her colleagues carried out several experiments in an attempt to understand what determines the anterior and posterior ends of a Drosophila larva (reviewed in C. Nüsslein- Volhard, H. G. Frohnhofer, and R. Lehmann. 1987. Science 238:1675– 1681). They isolated fruit flies with mutations in the bicoid gene (bcd−). These flies produced embryos that lacked a head and thorax. When they transplanted cytoplasm from the anterior end of an egg from a wild-type female into the anterior end of an egg from a mutant bicoid female, normal head and thorax development took place in the embryo. However, transplanting cytoplasm from the posterior end of an egg from a wild-type female into the anterior end of an egg from a bicoid female had no effect. Explain these results in regard to what you know about proteins that control the determination of the anterior–posterior axis.arrow_forwardhttps://ny.pbslearningmedia.org/resource/biot09.sci.life.gen.epigenetics/epigenetics/ In what way do the brown and yellow mice shown in the video differ?Why is this so?arrow_forward
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