HUMAN BIOLOGY
16th Edition
ISBN: 9781260233032
Author: Mader
Publisher: RENT MCG
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Chapter 21.3, Problem 3CYP
Explain why some incidences of autosomal recessive disorders are higher in one race or culture.
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Classify the following conditions based on whether they are describing autosomal dominance, autosomal recessive, or both.
Cystic fibrosis (CF) is an autosomal recessive condition triggered by the overproduction of sticky
mucus that clogs the lungs and pancreas. It is a life-threatening disease, but medical advances helped
the afflicted to live through adulthood.
The mother of Claudia died from cystic fibrosis, but her father was normal and never had any
relative with CF. Her fiancé, Marcus, turned out to be a carrier of the CF allele.
What are the genotypes of Claudia and Marcus?
Claudia: ________________________ Marcus: _____________________
They planned to have four children. What is the probability that:
a. all children will be normal
b. at least two will be normal
PLEASE SHOW COMPLETE SOLUTION
Explain why loss-of-function alleles often follow a recessivepattern of inheritance.
Chapter 21 Solutions
HUMAN BIOLOGY
Ch. 21.1 - Distinguish between a genotype and a phenotype.Ch. 21.1 - Define allele, gene, dominant, and recessive as...Ch. 21.1 - Prob. 3LOCh. 21.1 - Define the following terms:Â gene, allele, locus,...Ch. 21.1 - Prob. 2CYPCh. 21.1 - Prob. 3CYPCh. 21.2 - Prob. 1LOCh. 21.2 - Calculate the probability of a specific genotype...Ch. 21.2 - Prob. 1CYPCh. 21.2 - Prob. 2CYP
Ch. 21.2 - Using a dihybrid cross as an example (see Fig....Ch. 21.3 - Interpret a human pedigree to identify the pattern...Ch. 21.3 - Prob. 2LOCh. 21.3 - Solve the following: In a pedigree, all the...Ch. 21.3 - Prob. 2CYPCh. 21.3 - Explain why some incidences of autosomal recessive...Ch. 21.4 - Prob. 1LOCh. 21.4 - Prob. 2LOCh. 21.4 - Prob. 3LOCh. 21.4 - Prob. 1BTSCh. 21.4 - Prob. 2BTSCh. 21.4 - Prob. 1CYPCh. 21.4 - Prob. 2CYPCh. 21.4 - Discuss the potential evolutionary advantages of...Ch. 21.5 - Prob. 1LOCh. 21.5 - Prob. 2LOCh. 21.5 - Prob. 1CYPCh. 21.5 - Prob. 2CYPCh. 21.5 - Discuss why X-linked disorders are more common...Ch. 21.5 - Prob. 1BTSCh. 21.5 - Prob. 2BTSCh. 21 - Prob. 1ACh. 21 - 2. Which of the toll awing terms refers to...Ch. 21 - Prob. 3ACh. 21 - Prob. 4ACh. 21 - 5. The genotype of an individual with the dominant...Ch. 21 - Prob. 6ACh. 21 - Prob. 7ACh. 21 - Prob. 8ACh. 21 - Which of the following disorders is caused by a...Ch. 21 - Prob. 10ACh. 21 - Prob. 11ACh. 21 - Prob. 12ACh. 21 - Which of the following terms may be used to...Ch. 21 - Prob. 14ACh. 21 - Prob. 15ACh. 21 - Prob. 1TCCh. 21 - Prob. 2TCCh. 21 - Prob. 3TC
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Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- Cystic fibrosis (CF) is an autosomal recessive condition triggered by the overproduction of sticky mucus that clogs the lungs and pancreas. It is a life-threatening disease, but medical advances helped the afflicted to live through adulthood. Betty's mother died from cystic fibrosis, but her father was normal and never had any relative with CF. Her fiancé, Jones, turned out to be a carrier of the CF allele. What are the genotypes of Betty and Jones? 1. Betty: ________________________ 2. Jones: _____________________ They planned to have four children. What is the probability that: 3. all children will be normal 4. at least two will be normalarrow_forwardExplain the Autosomal Recessive Disorders ?arrow_forwardWhich of the following genetic diseases is/are inherited as an autosomal dominant trait: sickle cell anemia, hemophilia A, Huntington’s disease?arrow_forward
- Two affected daughters and two normal sons are born to an affected male and a normal female. Each of the affected daughters (and their normal husbands) gave birth to affected sons and daughters. Normal sons of the couple married normal women and had normal children. Which of the following is the most likely mode of inheritance for this trait?* Sex-linked recessive Sex-linked dominant Autosomal dominant Autosomal recessivearrow_forwardExplain the Pedigrees for Autosomal Disorders ?arrow_forwardWhich genotype is indicative of the carriers of a trait associated with an autosomal recessive inheritance pattern? Tt TT tt All of thesearrow_forward
- Cystic fibrosis (CF) is an autosomal recessive condition triggered by the overproduction of stickymucus that clogs the lungs and pancreas. It is a life-threatening disease, but medical advances helpedthe afflicted to live through adulthood.The mother of Claudia died from cystic fibrosis, but her father was normal and never had anyrelative with CF. Her fiancé, Marcus, turned out to be a carrier of the CF allele. What are the genotypes of Claudia and Marcus? Claudia: ________________________ Marcus: _____________________ They planned to have four children. What is the probability that: a. all children will be normal b. at least two will be normalarrow_forwardCystic fibrosis (CF) is an autosomal recessive condition triggered by the overproduction of stickymucus that clogs the lungs and pancreas. It is a life-threatening disease, but medical advances helpedthe afflicted to live through adulthood. The mother of Claudia died from cystic fibrosis, but her father was normal and never had anyrelative with CF. Her fiancé, Marcus, turned out to be a carrier of the CF allele. What are the genotypes of Claudia and Marcus? Claudia: ________________________ Marcus: _____________________ They planned to have four children. What is the probability that:a. all children will be normal b. at least two will be normalarrow_forwardDescribe the characteristics of a pedigree for an autosomal dominant and an autosomal recessive trait.arrow_forward
- List the characteristics of autosomal dominant and autosomal recessive pedigrees.arrow_forwardHuntington’s disease, a neurodegenerative genetic disorder that typically becomes noticeable in middle age, is due to an autosomal dominant allele. Sickle cell anemia, on the other hand, is a genetic blood disorder due to a recessive allele. Mary is a carrier of the allele for sickle cell anemia but has no sign of any neurodegenerative disorder in her family. She married Paul whose father died of Huntington’s disease. His mother, however, is not inflicted with that condition. Neither of his parents exhibits sickle cell anemia. What are the genotypes of Jane and Paul? If they plan to have four children, what is the probability that: all their children will be normal? _________________________________ they will have a son with Huntington’s disease? _________________________ they will have a daughter inflicted with both conditions?________________arrow_forwardTuberous Sclerosis (TS) is an autosomal dominant genetic disease characterized by seizures, mental retardation, autism, and benign tumors of the brain, heart, skin, and kidneys. The kidney tumors can also be malignant. This disease exhibits a wide range of severity, and only about 1/3 of the cases are inherited. Two different genes have been tightly linked to the disease in families where it is inherited. The remaining 2/3 appear to be due to mutations in one of the 2 genes as well. Overall it appears that 1/2 are caused by mutations in TSC1 and the other half by mutations in TSC2. A rat model for hereditary renal carcinoma (kidney cancer) has been found. Southern and Northern blot analysis of the TSC1 and TSC2 gene revealed no differences between these rats and normal rats. Not all the rats in the strain would get cancer but a significant proportion did and those were selected for and used in experiments. 1. a) What was detected by the Southern blots? (look this up, make your…arrow_forward
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