HUMAN BIOLOGY
16th Edition
ISBN: 9781260233032
Author: Mader
Publisher: RENT MCG
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Chapter 21.3, Problem 1CYP
Solve the following: In a pedigree, all the members of one family are affected. Based on this knowledge, list the genotypes of the parents (a) if the trait is recessive and (b) if the trait is dominant.
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Solve the following: In a pedigree, all the members of onefamily are affected. Based on this knowledge, list thegenotypes of the parents (a) if the trait is recessive and(b) if the trait is dominant.
Please consider the following pedigree. Assume that people who marry in to the family do not carry the allele unless otherwise indicated. Assume complete penetrance.
image attached
a. Is it possible for the inheritance pattern for the trait illustrated in this pedigree to be as a result of each of the following? Answer yes or no. (i) an autosomal recessive allele (AR)(ii) an autosomal dominant allele (AD)(iii) a X-linked recessive allele (XR)(iv) a X-linked dominant allele (XD) b. Provide a set of parents that definitively supports your answers in (a).
A couple who are about to get married learn from studying their family histories that, in both their families, theirunaffected grandparents had siblings with cystic fibrosis(a rare autosomal recessive disease).a. If the couple marries and has a child, what is theprobability that the child will have cystic fibrosis?b. If they have four children, what is the chance that thechildren will have the precise Mendelian ratio of 3:1 fornormal:cystic fibrosis?c. If their first child has cystic fibrosis, what is theprobability that their next three children will be normal?
Chapter 21 Solutions
HUMAN BIOLOGY
Ch. 21.1 - Distinguish between a genotype and a phenotype.Ch. 21.1 - Define allele, gene, dominant, and recessive as...Ch. 21.1 - Prob. 3LOCh. 21.1 - Define the following terms:Â gene, allele, locus,...Ch. 21.1 - Prob. 2CYPCh. 21.1 - Prob. 3CYPCh. 21.2 - Prob. 1LOCh. 21.2 - Calculate the probability of a specific genotype...Ch. 21.2 - Prob. 1CYPCh. 21.2 - Prob. 2CYP
Ch. 21.2 - Using a dihybrid cross as an example (see Fig....Ch. 21.3 - Interpret a human pedigree to identify the pattern...Ch. 21.3 - Prob. 2LOCh. 21.3 - Solve the following: In a pedigree, all the...Ch. 21.3 - Prob. 2CYPCh. 21.3 - Explain why some incidences of autosomal recessive...Ch. 21.4 - Prob. 1LOCh. 21.4 - Prob. 2LOCh. 21.4 - Prob. 3LOCh. 21.4 - Prob. 1BTSCh. 21.4 - Prob. 2BTSCh. 21.4 - Prob. 1CYPCh. 21.4 - Prob. 2CYPCh. 21.4 - Discuss the potential evolutionary advantages of...Ch. 21.5 - Prob. 1LOCh. 21.5 - Prob. 2LOCh. 21.5 - Prob. 1CYPCh. 21.5 - Prob. 2CYPCh. 21.5 - Discuss why X-linked disorders are more common...Ch. 21.5 - Prob. 1BTSCh. 21.5 - Prob. 2BTSCh. 21 - Prob. 1ACh. 21 - 2. Which of the toll awing terms refers to...Ch. 21 - Prob. 3ACh. 21 - Prob. 4ACh. 21 - 5. The genotype of an individual with the dominant...Ch. 21 - Prob. 6ACh. 21 - Prob. 7ACh. 21 - Prob. 8ACh. 21 - Which of the following disorders is caused by a...Ch. 21 - Prob. 10ACh. 21 - Prob. 11ACh. 21 - Prob. 12ACh. 21 - Which of the following terms may be used to...Ch. 21 - Prob. 14ACh. 21 - Prob. 15ACh. 21 - Prob. 1TCCh. 21 - Prob. 2TCCh. 21 - Prob. 3TC
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- In humans, the genetic disease cystic fibrosis is caused by a recessive allele (a). The normal (healthy) allele is dominant (A). What is the genotype of someone who has cystic fibrosis? What are the two different genotypes that a healthy person could have? If two people were both heterozygous for the cystic fibrosis gene, what fraction of their children would be likely to have this disease? Hint: Draw a Punnett square to figure it out.arrow_forwardThis pedigree (below) shows inheritance of a genetic disorder in a family. Assume the trait is rare. What is the mode of inheritance for this trait? [Select] You know this because that mode of inheritance is characterized by: [Select] individuals who have the allele express it and • An affected male parent passes the allele to [Select] and [Select] of his daughters. • An affected female parent passes the allele to sons and [Select] [Select] of her daughters. 1008 ㅇㅁㅇㄹ O ✓ of his sons of herarrow_forwardHere is a cat family. Back fur is created by BB or Bb. White by bb. Based on what the pedigree shows, is this trait recessive or dominant? How do you know? 6. a) b) (4 --1 per individual ) Label everyone's genotype. In some cases you may have to say there is an X probability of, for example, BB and a Y probability of Bb. Hint: these probabilities might not be in halves or fourths. c) baby? No qualifiers! (Don't say, if this certain individual was genotype X, then there is a A% probability, but if this individual was genotype Y, then there is a B% probability. (SHOW WORK) If siblings Il-1 and Il-2 mate, what is the total, overall probability that they will have a white kitten II 1 2arrow_forward
- Using the pedigree chart attached: Above is a pedigree for colorblindness. Based on the pedigree, is the disease dominant or recessive and is it sex-linked or autosomal? Why? Furthermore, what is the probability that 18 on this chart is affected but the condition, and what is the probability that 18 is a carrier? Why? Are the probability of being a carrier and an affected individual different? Why?arrow_forwardIn a testcross, the parent that is homozygous recessive for the genes being studied is called the testcross parent. The parent that has the dominant phenotype of the genes being studied is called the non-testcross parent.Which of the following is NOT a reason that a testcross is a useful technique when studying the inheritance of a trait? a. A testcross can determine if an individual with the dominant phenotype is homozygous or heterozygous. b. The relative frequencies of the different phenotypes among the testcross progeny can be used to map linked genes. c. Because the testcross parent can contribute only recessive alleles, the alleles contributed by the other parent will be expressed in the offspring of the testcross. d. The gametes produced by the testcross parent are determined from the testcross progeny.arrow_forwardConsider the following cross examining four gene in two parental line: Parent 1: A/a; B/B; D/d; E/e Parent 2: A/a; B/b; d/d; e/e Assuming independent assortment for the four genes, what fraction of progeny will be phenotypically identical to either parent 1 or parent 2? (Hint: first figure out the fraction of progeny that resembles parent 1 and parent 2 separately, then get the overall fraction.) 9/16 1/16 3/4 3/8 3/16arrow_forward
- Solve the following pedigrees:arrow_forwardThe pedigree below tracks the inheritance of a genetic disorder through a family's generation. Determine the probable inheritance mode for the trait shown in the affected individual (the shaded symbols) by answering the following questions. I II 2 3 4 5 7 III 2 3 6 7 8 5 (i) Based on the pedigree, Y-linked inheritance can be excluded at a glance. Give your reason. (ii) What TWO (2) other modes of inheritance can be definitely excluded? Explain your answer. Of the remaining modes of inheritance, which is the most likely? Which is less likely? Explain your answers. (ii)arrow_forwardThe pedigree shows a family in which several members have suffered from one and the same disease (look at the picture to be able to answer) a) Is it a dominant or recessive allele that causes the disease? Motivate your answer. b) Is allele autosomal or sex-linked? Motivate your answer. c) What is the probability that III-3 and III-4 will have a healthy child? Motivate your answer.arrow_forward
- Look at the pedigree below and answer the following questions related to the human genetic trait depicted in this pedigree. 1. Indicate whether the pattern of inheritance associated with this human trait is most likely to be (i) rare X-linked recessive, (ii) sex-influenced, or (iii) sex-limited. You may assume that the gene is fully penetrant. Then, provide a specific reason that justifies your selection of this pattern of inheritance as the correct one, and also explain why each of the other two alternatives are not correct. As part of your answer, include the phenotypic ratio, including the sex of the offspring, that you would expect to find in each of the three possible scenarios.arrow_forwardRed-green color blindness is inherited as an X-linked recessive (Xc). If a color-blind man marries a woman who is heterozygous for normal vision, what would be the expected phenotypes of their children with reference to this character? In your answer, specify in your phenotype descriptions the gender of the children. (For example, don’t just say 75% of the children would be colorblind – you would instead say 100 % of the daughters would be colorblind and 50% of the sons would be colorblind. Note that this is not a correct answer; it is just to give you an idea of how to explain the correct phenotypes of the cross.)___arrow_forwardWithout referring to the notation used to write the genotypes, how are you able to tell that a gene is inherited by: a. complete dominance (as described by Mendel)? b. incomplete dominance? c. codominance?arrow_forward
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Beyond Mendelian Genetics: Complex Patterns of Inheritance; Author: Professor Dave Explains;https://www.youtube.com/watch?v=-EmvmBuK-B8;License: Standard YouTube License, CC-BY