Campbell Biology
Campbell Biology
12th Edition
ISBN: 9780135188743
Author: Urry
Publisher: PEARSON
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Chapter 21, Problem 5TYU

EVOLUTION CONNECTION Genes important in the embryonic development ol animals, such as homeobox-coniaining  genes, have been relatlvely well conserved during evolution; that is. they are more similar among different species than are many other genes. Explain why this is.

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Rates of evolution appear to vary in different lin-eages. For example, the rate of evolution in the rat lineageis significantly higher than in the human lineage. Theserate differences are apparent whether one looks at changesin nucleotide sequences that encode proteins and are sub-ject to selective pressure or at changes in noncoding nucle-otide sequences, which are not under obvious selectionpressure. Can you offer one or more possible explanationsfor the slower rate of evolutionary change in the humanlineage versus the rat lineage?
Genes important in the embryonic development of animals, such as homeobox-containing genes, have been relatively well conserved during evolution; that is, they are more similar among different species than are many other genes. Explain why this is.
. a. If you found a zinc-finger domain (which facilitates DNA binding) in a newly identified gene,what kinds of hypotheses could you make aboutthe gene’s function?b. Suppose that this newly identified gene shares ahigh percentage of similarity throughout its lengthwith a previously characterized gene in the sameorganism. What does this fact suggest about the origin of the two genes? Would you categorize thesegenes as being: (i) homologous, (ii) paralogous, or(iii) orthologous? (More than one answer may apply.)

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