Biology
5th Edition
ISBN: 9781260487947
Author: BROOKER
Publisher: MCG
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Chapter 18, Problem 2TY
Summary Introduction
Introduction: A gene can be defined as a unit of inheritance of characteristics from the parent to its offspring. It helps in the transmission of characteristics across generations. The genes are comprised of
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In mice, the copy of the Igf2 gene that is inherited from the mother isnever expressed in her offspring. This happens because the Igf2 genefrom the mothera. always undergoes a mutation that inactivates its function.b. is deleted during oogenesis.c. is deleted during embryonic development.d. is not transcribed in the somatic cells of the offspring.
When comparing gene expression of the cells of the ICM and those of the trophoblast, which of the following is TRUE?
a. Cells of the trophoblast express Nanog.
b. Cells of the ICM and trophoblast will show the same gene expression pattern.
c. ICM cells express Cdx2.
d. Cells of the ICM express Oct 4
One example of an oncogene is ras. Ras is a G protein that is activated when growth factors bind to a G protein-coupled receptor. The mutated form of ras binds to GTP but does not allow the GTP to be broken down to GDP. Ras is involved in both the G1G1 and G2G2 checkpoints.
What happens to cells that have this mutated form of ras?
A.
They divide when they should not.
B.
They don’t divide when they should.
C.
They enter mitosis without going through the S phase of the cell cycle.
D.
They enter cytokinesis without going through the M phase of the cell cycle.
Chapter 18 Solutions
Biology
Ch. 18.2 - Prob. 1CCCh. 18.3 - Prob. 1CCCh. 18.3 - Prob. 1CSCh. 18.5 - Prob. 1CSCh. 18.5 - Prob. 1CCCh. 18.6 - Prob. 1EQCh. 18.6 - Prob. 2EQCh. 18.6 - Prob. 3EQCh. 18.6 - Prob. 1CCCh. 18.6 - Prob. 2CC
Ch. 18 - Which of the following is an example of an...Ch. 18 - Prob. 2TYCh. 18 - A female mouse that is Igf2 Igf2 is crossed to a...Ch. 18 - Prob. 4TYCh. 18 - Prob. 5TYCh. 18 - Prob. 6TYCh. 18 - Prob. 7TYCh. 18 - Prob. 8TYCh. 18 - Based on the ideas proposed by Morgan, which of...Ch. 18 - Extranuclear inheritance occurs because a. certain...Ch. 18 - Define epigenetics. Are all epigenetic changes...Ch. 18 - What is a Barr body? How is its structure...Ch. 18 - Core Concept: Information A core concept of...Ch. 18 - Prob. 1COQCh. 18 - Mendel studied seven traits in garden pea plants,...
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- A key event that initially determines female or male development in Drosophila is the a. transcription of the Sxl gene. b. alternative splicing of the Sxl pre-mRNA. c. expression of the ix gene. d. expression of the her gene.arrow_forwardWhich of the following statement(s) is/are true with regard to positional information in Drosophila? A. Morphogens are a type of molecule that conveys positional information. B. Morphogenetic gradients are established only in the oocyte, prior to fertilization. C. Cell adhesion molecules also provide a way for a cell to obtain positional information.arrow_forwardWhich of the following associated with cancer development would you expect to be tumor promoters and not genotoxic carcinogens (select all that apply)? A. Excessive alcohol consumption that kills liver cells B. Bisphenol A which mimics the activity of estrogen C. Chemical in pesticides that binds and activates a transcription factor that cause activation of NFkB D. Chemical in cigarette smoke that forms adduct with DNA E. A viral infection that causes ulcerative coilitis of GI tractarrow_forward
- Glucocorticoids are sterojd hormones that are released into the circulation and will cause changes to gene expression in the cells that respond. Which of the following would be a factor that can determine whether a cell will respond to circulating glucocorticoids? Whether the cell expresses the lac repressor. O A. O B. Whether the cell expresses the CREB protein. Whether the cell expresses the glucocorticoid receptor. C. Whether CAMP is produced at high levels by adenylyl cyclase. D. O E. Whether adenylyl cyclase is activated or not.arrow_forwardMutations in the BRCA genes have been shown to be related to a higher incidence of breast cancer in humans, and genetic tests are available that enable women to discover whether they carry versions of the gene associated with high risk. However, even early detection of breast cancer does not guarantee a cure. What considerations can you think of for and against advising women to take the tests? ·arrow_forwardProtein levels and mRNA levels for a particualr gene don’t always match. For example, the GCN4 gene in yeast is always producing mRNA, but the Gcn4 protein is only made when the cells are starved. B. What does this mean for diagnostic techniques that try to look at gene expression?arrow_forward
- In early mammalian development, compaction would likely be blocked by inhibiting expression of which of the following? a. Beta-catenin. b. E-cadherin. c. Bcl2. d. Cdx2.arrow_forwardDefects in this gene have been associated with metastasis in pancreatic cancer. Select one: O a. APC O b. RB O c. p53 O d. C-myc O e. Palladin O f. ras O g. BRCA1arrow_forwardMaster regulatory genes play critical roles in development. Predict the MOST likely fate of a fly embryo where master regulatory genes were nonfunctional due to mutation. A. Cell division would stop, and the embryo would halt development. B. The embryo would be a collection of undifferentiated cells because they never get the message that will send them down a determination pathway. C. The embryo would be a combination of differentiated and undifferentiated cells because, even in the absence of a functional master regulatory gene, some cells will differentiate on their own. D. The embryo would continue to develop, but there is a high probability that some limbs may end up in the wrong place in the adult.arrow_forward
- For the Igf2 gene, where do de novo methylation and maintenancemethylation occur?a. De novo methylation occurs in sperm, and maintenancemethylation occurs in egg cells.b. De novo methylation occurs in egg cells, and maintenancemethylation occurs in sperm cells.c. De novo methylation occurs in sperm, and maintenancemethylation occurs in somatic cells of offspring.d. De novo methylation occurs in egg cells, and maintenancemethylation occurs in somatic cells of offspring.arrow_forwardWhich of the following best describes the concept of cell differentiation during the development of a multicellular organism? A. During development, all of the genes in the embryo's cells are expressed at first, but fewer and fewer are expressed as time proceeds. B. During development, different sets of genes are deleted from different cell types so that at the end of development, each cell has only the genes it needs. C. During development, different cells become specialized to have different phenotypes even though they all originated from the same cell. ..arrow_forwardWhich of the following is NOT a way in which proto-oncogenes can change to become genes that induce cancer? Group of answer choices a. changes in a control element (enhancer) to increase transcription b. gene amplification c. changes in DNA sequence to produce a product that degrades rapidly d. movement of the gene adjacent to a different control element to increase transcription e. changes in DNA sequence to produce a product that isarrow_forward
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