Biology
5th Edition
ISBN: 9781260487947
Author: BROOKER
Publisher: MCG
expand_more
expand_more
format_list_bulleted
Videos
Question
Chapter 15.4, Problem 2CC
Summary Introduction
To explain: The relation between the expression of the bcr gene in white blood cells and the type of cancer caused by the translocation between chromosome number 9 and 22.
Introduction: The irregularities in the signaling pathway of cell division cause malfunctioning in the growth of the cell. The uncontrolled growth of the cell leads to cancer.. The agents that cause cancer are called “carcinogens.”
Expert Solution & Answer
Want to see the full answer?
Check out a sample textbook solution
Students have asked these similar questions
Question:
Explain how epigenetic marks and genomic imprinting are related. Provide a drawing to illustrate your point.
Research cancer mutation. Provide the link to the research article that gives you your information. One good resource to use is PubMed. Then answer the following questions, in 3 paragraphs, 3-5 sentences each.
1. What kind of disease/cancer does this mutation cause?
2.What happens during transcription to cause this mutation?
3. Is this trait passed on to progeny? Can the progeny be a carrier or simply affected?
In your own words:
Describe the molecular mechanisms involved in P53’s role as a tumor repressor protein.
Chapter 15 Solutions
Biology
Ch. 15.1 - Consequences of Mutations Concept Check: Based on...Ch. 15.1 - Prob. 2CCCh. 15.2 - Prob. 1EQCh. 15.2 - Prob. 2EQCh. 15.2 - Prob. 3EQCh. 15.2 - Prob. 1CCCh. 15.3 - DNA Repair Concept Check: Which components of the...Ch. 15.3 - Why is this person so sensitive to sunlight?...Ch. 15.4 - Prob. 1CCCh. 15.4 - Prob. 2CS
Ch. 15.4 - Prob. 2CCCh. 15.4 - Prob. 3CCCh. 15.4 - Prob. 4CCCh. 15 - Prob. 1TYCh. 15 - Prob. 2TYCh. 15 - Prob. 3TYCh. 15 - Prob. 4TYCh. 15 - Prob. 5TYCh. 15 - The Ames test a. provides a way to determine if...Ch. 15 - Xeroderma pigmentosum a. is a genetic disorder...Ch. 15 - Prob. 8TYCh. 15 - Prob. 9TYCh. 15 - Prob. 10TYCh. 15 - Prob. 1CQCh. 15 - Prob. 2CQCh. 15 - Prob. 3CQCh. 15 - Prob. 1COQCh. 15 - Distinguish between spontaneous and induced...
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- Which statements are true? Explain why or why not.1 In terms of the way it interacts with DNA, thehelix–loop–helix motif is more closely related to the leu-cine zipper motif than it is to the helix–turn–helix motif.2 Once cells have differentiated to their final spe-cialized forms, they never again alter expression of theirgenes.3 CG islands are thought to have arisen during evo-lution because they were associated with portions of thegenome that remained unmethylated in the germ line.4 In most differentiated tissues, daughter cells retaina memory of gene expression patterns that were presentin the parent cell through mechanisms that do not involvechanges in the sequence of their genomic DNA.arrow_forwardGenetic instability in the form of point mutations, chromosome rearrangements, andepigenetic changes needs to be maximal to allow the development of cancer.(a) With diagrams explain:(i) point mutations (ii) chromosome rearrangement (iii) epigenetic changesarrow_forwardHi, can you elaborate about the following: certain characterize mutations in p63 and compare that to known mutations in p53.arrow_forward
- Genetic instability in the form of point mutations, chromosome rearrangements, and epigenetic changes needs to be maximal to allow the development of cancer. (a) With diagrams explain, chromosome rearrangementarrow_forwardQuick help!!! Answer the following questions Only in cell biology 1. A. Discuss the roles of two main types of genes that are critical in cancer? B. What is the difference between a totipotent and a pluripotent stem cell? Give an example to each.arrow_forwardDisdis -how do RB and p53 negatively regulate the cell cycle in G1? describe the events that occur in the initiation and elongation of DNA replication in S phase.arrow_forward
- Cancer cells typically lose cell cycle entry control. Explain how the following mutations, which are found in some cancer cells, lead to a bypass of these controls: (a) overexpression of cyclin D, (b) loss of Rb function, (c) loss of p16 function, (d) hyperactive E2F.arrow_forwardGenetic instability in the form of point mutations, chromosome rearrangements, and epigenetic changes needs to be maximal to allow the development of cancer. (a) With diagrams explain point mutationsarrow_forwardA gene that codes for a positive cell-cycle regulator is called a(n).______ kinase inhibitor tumor suppressor gene proto-oncogene oncogene.arrow_forward
- Question : Give an alternative form of CpG methylation, given clear handwritten explaination!arrow_forwardDescribe error prone polymerases and the process of translesion synthesis (TLS). In regards to tumor biology, what is the mutator phenotype hypothesis? What are some ways in which error-prone polymerases could be targeted for potential anti-cancer treatments?arrow_forwardMacmillan Learning across generations. Place the events in the order necessary for an epigenetic modification to be inherited in the next generation. $ 4 900 F4 Certain CpG methylation sites are not erased during gametogenesis or embryogenesis. DNA methyltransferase recognizes and binds CpG sites on DNA. A methyl group is added to the cytosine residue of the DNA sequence. DNA methyltransferase maintains the methylation pattern on both DNA strands. % Recent studies have found instances of transgenerational inheritance of epigenetic traits in humans (Relton et al., 2012 already possess their eggs at birth whereas males do not produce sperm until nuberty For enigenetic modifications to 5 F5 ^ Methylated CpG sites on one inherited DNA strand 6 Epigenetic silencing passed to offspring F6 MacBook Air Answer Bank & 7 F7 * 8 DII. F8 DD F9 F10 J F11 Uarrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
Biology: The Dynamic Science (MindTap Course List)BiologyISBN:9781305389892Author:Peter J. Russell, Paul E. Hertz, Beverly McMillanPublisher:Cengage Learning
Biology 2eBiologyISBN:9781947172517Author:Matthew Douglas, Jung Choi, Mary Ann ClarkPublisher:OpenStax
Biology: The Dynamic Science (MindTap Course List)
Biology
ISBN:9781305389892
Author:Peter J. Russell, Paul E. Hertz, Beverly McMillan
Publisher:Cengage Learning
Biology 2e
Biology
ISBN:9781947172517
Author:Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:OpenStax
What are Mutations and what are the different types of Mutations?; Author: Science ABC;https://www.youtube.com/watch?v=I16YlE8qTBU;License: Standard youtube license