Biology
Biology
5th Edition
ISBN: 9781260487947
Author: BROOKER
Publisher: MCG
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Chapter 15, Problem 7TY

Xeroderma pigmentosum

  1. a. is a genetic disorder that results in uncontrolled cell growth.
  2. b. is a genetic disorder in which the NER system is not fully functional.
  3. c. is a genetic disorder that results in the loss of pigment in certain patches of skin.
  4. d. results from the lack of DNA polymerase proofreading.
  5. e. both b and d are true of this disorder.
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Which of the following are characteristics of aging cells (select all that apply)? A. Chronic inflammation results in premature shortening of telomeres B. Lengthening of telomeric DNA sequence C. Accumulation of telomere-dysfunction–induced foci (TIFs) D. Older cells produce more telomerase E. Increased erosion of telomeres
a. Which gene is mutated in individuals with sickle-cell anemia? b. What are the major symptoms of this disorder? c. What was the first published scientific description of sickle-cell anemia? d. Describe two other features of this disorder that you learned from the OMIM database and state where in the database you found this information

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