Essentials of Human Anatomy & Physiology (12th Edition)
12th Edition
ISBN: 9780134395326
Author: Elaine N. Marieb, Suzanne M. Keller
Publisher: PEARSON
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Chapter 15, Problem 13SAE
Summary Introduction
To review:
The pathway followed by a uric acid molecule in the kidney, from a glomerulus to the urethra.
Introduction:
The kidney is an important organ of the urinary system, which filters nitrogenous waste such as urea, ammonia, and uric acid in the body. Nephrons in the kidney filter all these waste products, which are then excreted out of the body. Uric acid is one of the waste materials released during purine degradation. When urine is highly concentrated in uric acid, it forms crystals that are called renal calculi.
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The presence of either protein or glucose in a urinalysis is abnormal, but these two molecules end up in the urine for different reasons. For each of these molecules, briefly describe where in the urine production process (i.e., glomerular filtration, tubular reabsorption or tubular secretion) the problem occurs, and why it might happen.
Which of the following pathways best describe the structures which urine has to flow through before being excreted out of the body? (Hint: some structures may be omitted, so just make sure the general order is correct)
1-Collecting duct -> bladder -> ureter
2-Collecting duct -> ureter -> bladder -> urethra
3-Collecting duct -> urethra -> bladder -> ureter
4-Major calyx -> minor calyx -> renal pelvis -> urethra
The process of hydrogen ion secretion in the proximal convoluted tubule occurs via which of the following mechanisms?
Choose from the following:
(A) hydrogen ions diffuse out of the glomerular filtrate of the proximal convoluted tubule, through extracellular fluid and into the peritubular blood
(B) carbon dioxide diffuses into the proximal convoluted tubule cell from peritubular capillary blood; undergoes a chemical reaction to form carbonic acid; dissociates into hydrogen and bicarbonate ions; the hydrogen ion diffuses into the glomerular filtrate of the proximal convoluted tubule
(C) hydrogen ions diffuse out of the peritubular capillary blood, through extracellular fluid and into the filtrate of the proximal convoluted tubule
(D) carbon dioxide diffuses into the proximal convoluted tubule cell from the glomerular filtrate; undergoes a chemical reacdtion to form carbonic acid; dissociates into hydrogen and bicarbonate ions; the hydrogen ions diffuse into the peritubular blood
Chapter 15 Solutions
Essentials of Human Anatomy & Physiology (12th Edition)
Ch. 15 - More than one choice may apply. Microscopic...Ch. 15 - Prob. 2MCCh. 15 - Urine passes through the ureters by which...Ch. 15 - Effects of aldosterone include a. increase in...Ch. 15 - 5. Which of the following is dependent on tubular...Ch. 15 - Prob. 6MCCh. 15 - The smallest fluid compartment is the a....Ch. 15 - Prob. 8MCCh. 15 - Prob. 9SAECh. 15 - Prob. 10SAE
Ch. 15 - Prob. 11SAECh. 15 - 12. About 150 L of plasma filters into the renal...Ch. 15 - Prob. 13SAECh. 15 - Prob. 14SAECh. 15 - Besides ridding the body of wastes formed during...Ch. 15 - Prob. 16SAECh. 15 - Prob. 17SAECh. 15 - Prob. 18SAECh. 15 - Prob. 19SAECh. 15 - Prob. 20SAECh. 15 - Prob. 21SAECh. 15 - Why is urinalysis a routine part of any good...Ch. 15 - 23. How do the internal and external urethral...Ch. 15 - Prob. 24SAECh. 15 - 25. What sometimes happens when urine becomes too...Ch. 15 - Define incontinence.Ch. 15 - Contrast the following homeostatic imbalances:...Ch. 15 - Why is cystitis more common in females?Ch. 15 - 29. What type of problem most commonly affects the...Ch. 15 - Prob. 30SAECh. 15 - Prob. 31CTCh. 15 - 32. Mitchell’s parents bring him to the clinic...Ch. 15 - A young woman has come to the clinic with dysuria...Ch. 15 - 34. What happens to the rate of RBC production in...Ch. 15 - Two physiology students are having a disagreement...Ch. 15 - Mr. Jessup, a 55-year-old man, is operated on for...Ch. 15 - 37. Raymond is hypertensive and was recently...
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- Now, consider a molecule of antibiotic that is secreted from the peritubular capillaries into the filtrate at the proximal tubule. Trace the pathway this antibiotic molecule would take from the renal artery to the point at which it exits the body of a female in the urine.arrow_forwardThe presence of either protein or glucose in a urinalysis is abnormal but they end up in the urine for different reasons. For each of these molecules, briefly describe where in the urine production process (i.e., glomerular filtration, tubular reabsorption or tubular secretion) the problem occurs, and why it might happen. please helparrow_forwardDraw a schematic diagram showing the flow of water and salts in the proximal tubule of the kidney. In this diagram, put the lumen on the left side of the diagram and the extracellular fluids on the right side of the diagram. Indicate where the lumen is, where the extracellular fluid is, where the apical portion of the cell is, and show the location of the proteins that are responsible for the movement of water and salts and glucose reabsorption in this area of the kidneyarrow_forward
- From what you have learned at this point about the nephron, it should now be obvious that the glomerular filtrate is not the same as the urine that is eventually formed. It is also important to note that many processes that glomerular filtrate goes through will vary depending on the state of the body and its need to maintain, among others, fluid or electrolyte balance. Make a concept map of the diluting and concentrating mechanisms of the kidneyarrow_forwardAlthough the kidneys are probably best known as filtration organs, tubular reabsorption (the second step of urine formation in a nephron) actually reclaims molecules that have already been filtered from the blood. Describe the tubular reabsorption process, including the structures and molecules involved, and explain why these molecules need to be reabsorbed. please helparrow_forwardTrace the path taken by the renal filtrate (and urine) from the glomerulus to the urethra. Name every microscopic and gross tube and structure that it passes through on its journey.arrow_forward
- Water though Urinary System Trace the path of the water molecule as it moves from this starting point to this ending point. Starting point: The water molecule enters a kidney in the blood plasma traveling through the renal artery. Ending point: The water molecule is excreted from the body. You may write a description, create a diagram with labels, or both to trace a path. Include as many of the following components of the urinary system and terms as you can: afferent arteriolecollecting ductdistal convoluted tubuleglomerular capsuleglomerulusmajor calyxminor calyx nephron loopproximal convoluted tubulerenal pelvisureterurethra For each of the parts of the urinary system in your path, describe a unique anatomical characteristic (size, tissue composition, etc.) or function.arrow_forwardThe renal handling of a novel drug is being studied. When the drug is present in the blood, it is filtered into the Bowman’s capsule and secreted via transport proteins in the renal tubules, but it is NOT reabsorbed. The lines on the following graph represent filtration, secretion and excretion rates of this drug at various plasma concentrations. For the three lines shown (labeled A-C) identify which line represents filtration, which line represents secretion, and which line represents excretion Explain how you determined this.arrow_forwardName the phenomenon of removal of uric acid as excretory product.arrow_forward
- Which of the following associations is correct? * Parietal layer of glomerular Capsule - Part of the filtration membrane Proximal convoluted tubule - Simple cuboidal epithelium with microvilli Glomerulus - Receives blood from the afferent arteriole Visceral layer of glomerular Capsule - Contains podocytes Loop of Henle - Helps create the osmolarity gradient in the renal medullaarrow_forwardList the steps by which the renal tubule achieves its functionarrow_forwardUrine is not about eliminating water accumulating directly in the urinary bladder. It is instead a very sophisticated process that involves the collaboration of two systems during various phases. Discuss in great detail the urine formation steps.arrow_forward
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