Becker's World of the Cell (9th Edition)
9th Edition
ISBN: 9780321934925
Author: Jeff Hardin, Gregory Paul Bertoni
Publisher: PEARSON
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Chapter 14, Problem 14.8PS
QUANTITATIVE Tipped Off. Polarized cytoskeletal structures and intraflagellar transport (IFT) are involved in formation of cilia and flagella.
(a) Observation of flagella in the biflagellate alga Chlamydomonas reinhardtii indicates that tubulin subunits and other flagellar materials move toward the tips of flagella at a rate of 2.5 μm/min, but materials moving back toward the base of flagella move at 4 μm/min. How do you explain this difference in rate of movement?
(b) Temperature-sensitive mutations in a kinesin II required for intraflagellar transport (IFT) have been identified in Chlamydomonas. Such mutations only lead to defects when the temperature is raised above a certain threshold, called the restrictive temperature. When algae with fully formed flagella are grown at the restrictive temperature, their flagella degenerate. What can you conclude about the necessity of IFT from this experiment?
(c) Based on your knowledge of the directionality of microtubule motors and the information in (b), where would you predict that the plus ends of flagellar microtubules are? State your reasoning.
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Problem. In a practical session, students studied a stained blood smear of a mouse with bacteria that were phagocytosed by leukocytes.
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Cleavage
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Precursor
Receptor
Inactive
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Active
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6. The figure above shows a model of a ligand precursor being cleaved to produce an active
ligand that binds to a specific receptor. Which of the following is most likely to reduce the
binding of the active ligand to its receptor?
(A) A change in the cytoskeletal attachment of transmembrane proteins
(B) The presence of a large amount of the precursor form of the ligand
(C) An increase in the ratio of the number of unsaturated to the number of saturated
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(D) A mutation in the receptor gene that causes a substitution of a charged amino acid for a
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different concentrations. Identify if the solutions in the beakers are Isotonic, hypertonic or hypotonic
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HOMEWORK
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11
Chapter 14 Solutions
Becker's World of the Cell (9th Edition)
Ch. 14 - If myosin V moved more like an inchworm (meaning...Ch. 14 - Kinesins and dyneins are both microtubule-based...Ch. 14 - CONCEPT CHECK 14.2 Human sperm swim using a...Ch. 14 - A single myosin II motor domain can exert about 15...Ch. 14 - Prob. 14.4CCCh. 14 - In addition to being found at the rear of...Ch. 14 - Ciliobrevins. Ciliobrevins were reported in 2012...Ch. 14 - Prob. 14.2PSCh. 14 - Prob. 14.3PSCh. 14 - Rigor Mortis and the Contraction Cycle. After...
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