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(a)
Interpretation:
Mechanism of compound are synthesized by the use of only provided carbon-containing compounds has to be given.
Concept introduction:
Required compounds are synthesized by the use of only provided carbon-containing compounds through a series of steps.
In first case, given alcohol is oxidized to a
In second case, given alcohol is oxidized to a ketone. A strong base is added to the ketone. Aldol condensation reaction takes place. Hydrazine in alcoholic potassium hydroxide is added in the aldol condensation product to remove the carbonyl group. The intermediate
In third case, ethanol is oxidized to acetaldehyde. Acetaldehyde undergoes aldol addition reaction in presence of a strong base. Aldol addition product is reduced to form a
(b)
Interpretation:
Mechanism of compound are synthesized by the use of only provided carbon-containing compounds has to be given.
Concept introduction:
Required compounds are synthesized by the use of only provided carbon-containing compounds through a series of steps.
In first case, given alcohol is oxidized to a ketone. A strong base is added to the ketone. Aldol condensation reaction takes place. The aldol product is reduced and the final compound is obtained.
In second case, given alcohol is oxidized to a ketone. A strong base is added to the ketone
Aldol condensation reaction takes place. Hydrazine in alcoholic potassium hydroxide is added in the aldol condensation product to remove the carbonyl group. The intermediate alkene is reduced to give the final compound.
In third case, ethanol is oxidized to acetaldehyde. Acetaldehyde undergoes aldol addition reaction in presence of a strong base. Aldol addition product is reduced to form a diol compound 1. Other alcohol is oxidized to an acetone and converted to diol compound 2. Compound 1 and 2 combine to form the final product and two molecules of water are reduced.
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Chapter 13 Solutions
Essential Organic Chemistry, Global Edition
- 5. Describe an efficient synthesis of 1-methyl-1-cyclohexanol from cyclohexanol. Show the structure of the reagents, reactants and products from each step. Cyclohexanol -------> -----> 1-methyl-1-cyclohexanolarrow_forwardSynthesize the product from the given material. Give the reagents necessary and draw out any intermediate products along the way.arrow_forwardCan you draw the mechanism for the synthesis of cyclohexene from cyclohexanol through an acid-catalyzed dehydration reaction. Where Phosphoric acid donates a proton ((H^+)) to the hydroxyl group of cyclohexanol, forming a protonated cyclohexanol intermediate. • The protonated cyclohexanol undergoes dehydration, leading to the removal of a water molecule and the formation of cyclohexene. • The released proton combines with water to form hydronium ion (H3O+), regenerating the catalyst. The mechanism should illustrate the acid-catalyzed dehydration process, where phosphoric acid facilitates the removal of water from cyclohexanol, resulting in the formation of cyclohexene.arrow_forward
- Determine the major product of the reaction shown in the box د b C A B C NaBH CH₂OH Select an answer and submit. For keyboard navigation, use the up/down arrow keys to select an answer. d D OH OH B ON OH C b Darrow_forwardBe sure to answer all parts. Complete the reactions to show the synthesis of the following product for the given reactant. OH OH ?1 ?2 OH HO draw structure major intermediate product Select the correct reactant(s) for ?1 H,0 O H,SO, 4. [1] BH3 NaOH [2] H,0, НО Select the correct reactant(s) for ?2 H,SO4 O [1] BH3 [2] Н,О,, НО NAOH HCIarrow_forwardWhat reagents are needed to carry out the following syntheses?arrow_forward
- Choose all reagent(s) that would lead to the product formation from the shown reaction. OH O H;SO4 BH3 in THE NaOHarrow_forwardSynthesize the product shown from the starting materials, including intermediates formed at each steparrow_forwardNonconjugated , -unsaturated ketones, such as 3-cyclohexenone, are in an acid-catalyzed equilibrium with their conjugated , -unsaturated isomers. Propose a mechanism for this isomerization.arrow_forward
- Give the product. NO ₂ 0 HNO ₂ H₂SO4arrow_forwardGive the main organic product for the following reaction: CH2OH OH H3O* CH3CH2CH2OH OH OHarrow_forwardDuring multistep syntheses, reduction reactions are often performed. Functional groups react differently with these reagents. With this in mind, draw the structure of the product of this reaction: NH2 NH2 LIAIH4 OH HO2C CO2H ČO2H For your convenience, the starting material has been drawn for you in the sketchpad. P aste opy C NH2 NH2 OH HO, HOarrow_forward
