Essential Organic Chemistry, Global Edition
Essential Organic Chemistry, Global Edition
3rd Edition
ISBN: 9781292089034
Author: Paula Yurkanis Bruice
Publisher: PEARSON
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Chapter 13, Problem 32P
Interpretation Introduction

Interpretation: Moles of malonyl-CoA required for the synthesis of one mole of Arachidic  acid has to be determined.

Concept introduction:

Fatty acids are aliphatic mono-carboxylic acids that are mostly obtained from the hydrolysis of natural fats and oils. They have a general formulaEssential Organic Chemistry, Global Edition, Chapter 13, Problem 32P , n is mostly an even number of carbon atoms (4 to 20) with a few exceptions that have an odd number.

In the synthesis of fatty acids, firstly acetyl thioester and malonyl thioester combines to form a four carbon thioester.  This thioester reacts with malonyl thioester.  Each malonyl thioester adds two carbon.  Each time malonyl thioester is added, two carbon atoms are increased in the fatty acid chain.

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Essential Organic Chemistry, Global Edition

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