Chapter 12.4, Problem 32AQP

Summary Introduction

To determine:

The results that would be expected in the experiment given in “Figure 12.17 (Experimental procedure for studying how nucleosomes dissociate and reassociate in the course of replication)”, as if all the original histone proteins remained on one strand of the DNA and new histone attached to the other strand.

Introduction:

If histone protein makes complexes with eukaryotic DNA, it leads to form nucleosome assembly. Nucleosomes are contributing to the stability and packaging of DNA. During replication, the structure of histone protein disrupted by the replication fork, however, in a short time duration nucleosomes reassembled on the newly synthesized strands of DNA.