Campbell Essential Biology (7th Edition)
7th Edition
ISBN: 9780134765037
Author: Eric J. Simon, Jean L. Dickey, Jane B. Reece
Publisher: PEARSON
expand_more
expand_more
format_list_bulleted
Question
Chapter 11, Problem 15IMT
Summary Introduction
To determine:
The major theme among the relationship of structure to function, information flow, pathways that transform energy and matter, interactions within biological system and evolution, which is evident and related with statement “ master control genes regulate other genes that determine what body parts will develop in which locations”.
Introduction:
Homeotic genes are regulatory genes that determine where certain anatomical structures, such as leg or wing will develop in an organism during morphogenesis. These are the master gene of development and can act as switches for other genes.
Expert Solution & Answer
Want to see the full answer?
Check out a sample textbook solutionStudents have asked these similar questions
LO: Explain how mutations in regulatory regions of genes differ from mutations in coding region
The presence or absence of pelvic spines in the stickleback fish is controlled by whether the Pitx1 gene is expressed in the pelvic tissue. The Figure below shows how Pitx1 transcription is regulated in different tissues. The center image is that of a stickleback embryo. The drawings in the surrounding boxes show the Pitx1 gene region and activator proteins present in the jaw, pelvis, eye, or pituitary tissues. While the diagram only shows one activator in one tissue, many activators are present in a particular tissue at any one time.
Activator molecules with specific shading can bind to switches with the same shading.
3a) Based on the diagram, in which tissues will the PitX1 gene be expressed?
3b) Assume a fish inherits a deletion mutation in the pituitary switch/enhancer sequence. You isolate DNA from jaw, pelvic, eye, and pituitary tissues. In the DNA of which tissue(s) would…
This is one given problem on my homework assignment for developmental biology. Thank you for the help!Describe the effects of FGF and RA on each other in limb bud development. Give a specific example of their effects on each other in this capacity. Knowing this, propose a question/hypothesis to investigate the mechanism of how a specific morphogen controls pattern if you know that the morphogen is both necessary and sufficient AND is expressed in the correct spatial/temporal frame.
WRT is a gene in C. elegans worms which is normally expressed in a specific stage of development.
Worms without this gene (wrt-/wrt- genotype) survive, but grow too large, never develop some
parts of their anatomy. Over-expression of WRT results in a different phenotype: the worms have
stunted growth, developing mature anatomical structures too early in their growth. The following
experiments were used to learn how WRT is regulated.
a.
Several genetic loci that are also involved in development in the worm are suspected of being
regulators of WRT. Mating experiments shows that some of these genes have epistatic
relationships with WRT, and others don't. Which are likely to be WRT regulators?
i. Genes epistatic to WRT are unlikely to regulate WRT
ii. Genes epistatic to WRT are likely to regulate WRT
iii. Epistasis cannot tell us whether another gene is in the same pathway as WRT
b. Deletion of locus 1 in a WRT wildtype background causes the wrt- associated phenotype (large
but…
Chapter 11 Solutions
Campbell Essential Biology (7th Edition)
Ch. 11 - Your bore cells, muscle cells, and skin cells look...Ch. 11 - A group of prokaryotic genes with related...Ch. 11 - The regulation of gene expression must be more...Ch. 11 - A eukaryotic gene was inserted into the DNA of a...Ch. 11 - How does DNA packing in chromosomes prevent gene...Ch. 11 - What evidence demonstrates that differentiated...Ch. 11 - The most common procedure for cloning an animal is...Ch. 11 - Prob. 8SQCh. 11 - Prob. 9SQCh. 11 - Prob. 10SQ
Ch. 11 - What is the difference between oncogenes and...Ch. 11 - Prob. 12SQCh. 11 - For each statement, identify which major theme is...Ch. 11 - For each statement, identify which major theme is...Ch. 11 - Prob. 15IMTCh. 11 - Study the depiction of the lac operon in Figure...Ch. 11 - The human body has a far greater variety of...Ch. 11 - Because a cat must have both orange and non-orange...Ch. 11 - Design a DNA microarray experiment that measures...Ch. 11 - Interpreting Data Review Figure 11.22 We can...Ch. 11 - A chemical called dioxin present in Agent Orange,...Ch. 11 - There are genetic tests for several types of...
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- provide one example from the Drosophila AP toolkit for "Toolkit genes can be classified according to the phenotypes caused by their mutation. Similar mutant phenotypes often reflect genes that function in a single developmental pathway. Distinct pathways exist for the generation of body axes, for example, and for the formation and identity of fields."arrow_forwardexamine the process of gene expression. Include the following: Explain the regulation of gene expression in eukaryotic cells. Discuss mechanisms by which gene expression may be altered. How do these alterations induce cancer-causing mutations in cell DNA? Explain how cancer is formed. Describe genetic changes found in cancer cells and how these changes lead to alterations in cell behavior. Determine whether proteome data can be utilized in genetic disorder diagnosis. Relate the Human Genome Project data to the analysis of cancer genes. Relates the Human Genome Project's utility in pharmacogenomics and personalized medicine to diagnose and treat cancerarrow_forward(2) Design an experiment on how would molecular genetic tools, such as DNA microarrays, be used to study human diseases, such as skin tumor cell growth or migration? How could they be used to study melanin expression in nomal skin cells? Rubric for Class Portfolio #1: Student creates an experiment with experimental and negative control group on hoW DNA microarrays can used to address how it can be used to monitor skin tumor cell growth and/or migration, as well as melanin gene expression.arrow_forward
- Developmental abnormalities can result from: 1. Under expression of some genes 2. All of these choices are correct 3. Inappropriate interaction among gene products that were expressed in the wrong amounts and wrong time 4. Over expression of some genes 5. corrupted timing of the normal time genes are expressedarrow_forwardIn which tissue(s) is the mRNA and protein highly expressed in? 1. Go to: https://www.proteinatlas.org/2. Type the name of your protein in the search bar. Click "Search"3. Click on the gene name of your protein4. Click on the "Tissue" icon5. Scroll down to the graphs showing Protein and mRNA expression.6. Search for the tissue type that shows high expression in both the protein and mRNA graphs. Kidney Placenta Adipose tissue Stomach Ovary *Can be more than one answer*arrow_forward* Google Translate x + re.com/courses/49703/quizzes/244266/take/questions/5315835 Understanding BAC-23 better might be the difference in curing cancer and saving millions of lives! You must sequence its genome and find the genetic code that makes the cancer curing protein. After running several tests, you have found the correct gene segment to be: GGG UCG ACA CUC UUU. Remember that bacteria are weird and their genes are made from a single strand with ribose sugar backbones! 1. Give the correct DNA template for this bacterial gene segment (GGG UCG ACA CUC UUU). ***Please use the following format or it will be marked incorrect*** Example: ABC DEF GHI JKL MNO, all caps, organized in threes with a space in between. Please make my life easier 2. Using the genetic code provided (GGG UCG ACA CUC UUU), translate this gene segment. ***Please use the following format or it will be marked incorrect*** Example: ABC DEF GHI JKL MNO, all caps, organized in threes with a space in between. Please make…arrow_forward
- Locate a gene expression data set on Gene Expression Omnibus using "expression by hybridization" involving Rabies virus or related virus Use GEO2R to perform pairwise group analysis Explore and identify the most regulated genes: gene/protein functions of Rabies virusand Define the significance of these genes/proteins in the disease process.arrow_forwardConcept test: Please discuss thoroughly. The easily observed external structures in insects, such as different pairs of legs, antennae, and wings form from imaginal discs. a.) How is the identity of the different Drosophila imaginal discs established in the embryo—for example, how is it determined whether a disc will form a wing, a leg, or some other structure? b.) Dominant mutants in the gene Antennapedia result in fore legs forming in the location where antennae are expected. How does this mutant phenotype illustrate your response to Part a?arrow_forwardCancer stem cells (CSCs) are cancer cells (found within tumors or hematological cancers) that possess characteristics associated with normal stem cells, specifically the ability to give rise to all cell types found in a particular cancer sample. There are many biomedical engineering based approaches to detect CSCs. Question: What kind of systems have been developed to detect CSCs? Describe by giving examples. Please explain in detail the main findings with your own words.arrow_forward
- "In most differentiated tissues, daughter cells retain a memory of gene expression patterns that were present in the parent cell through mechanisms that do not involve changes in the sequence of their genomic DNA" is true or false.arrow_forwardThe C-myc gene is a proto-oncogene which is highly expressed in breast tissue and appears to cause proliferation of breast tissue and its elevated expression is associated with breast cancer. Based just on the ChIP data from the previous questions (also shown below), which of the three drugs (estrogen, tamoxifen and raloxifene) would you recommend for treating breast cancer? Justify your response and explain the potential side effects of each drug.arrow_forwardHuntington disease (HD) is an inherited neurodegenerative disorder characterized by gradual, irreversible impairment of psychological, motor, and cognitive functions. Symptoms typically appear in middle age, but onset can occur at almost any age, and the course of the disease can range from 15 to 20 years. The molecular basis of HD is becoming better understood, and the genetic mutation has been traced to a gene that encodes a large protein of unknown function. In individuals who will not develop HD, a region of the gene that encodes the N-terminus of this protein has a sequence of CAG codons (for glutamine) repeated 6 to 39 times in succession. In individuals with adult-onset HD, this codon (3 nucleotides) is typically repeated 40 to 55 times In those with childhood-onset HD, it is repeated more than 70 times. *codon: refers to the 3 nucleotides that code for amino acid. A small portion of the coding sequence of the HD gene is given below. The nucleotide sequence of the DNA is…arrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
- Human Heredity: Principles and Issues (MindTap Co...BiologyISBN:9781305251052Author:Michael CummingsPublisher:Cengage Learning
Human Heredity: Principles and Issues (MindTap Co...
Biology
ISBN:9781305251052
Author:Michael Cummings
Publisher:Cengage Learning
What are Mutations and what are the different types of Mutations?; Author: Science ABC;https://www.youtube.com/watch?v=I16YlE8qTBU;License: Standard youtube license