provide one example from the Drosophila AP toolkit for "Toolkit genes can be classified according to the phenotypes caused by their mutation. Similar mutant phenotypes often reflect genes that function in a single developmental pathway. Distinct pathways exist for the generation of body axes, for example, and for the formation and identity of fields."

At the molecular level, how do you think a gain-of-function mutation in a developmental gene might cause it to be expressed in the wrong place or at the wrong time? Explain what type of DNA sequence would be altered.

Include a description as to why disrupting the expression of each gene leads to the phenotype observed of C.Elegans bli-1, dpy-10, rol-6, unc-22, egl-1 and pos-1

After graduating from UNC Charlotte with the BS in Biology, you get a job with an agro-chemical company and are assigned to a lab that is exploring the use of a newly synthesized compound that may be a possible insecticide. The compound is thought to control insect populations by disrupting the genes that control embryonic development. Your lab conducts an experiment to investigate the influence of the compound on developmental genes by measuring the levels of the proteins the genes code for.  You measure protein levels in two groups of insect eggs: the Treatment Group, which is exposed to the compound, and the Control Group, which is exposed to a compound that is known to have no negative effects on gene activity. Your results are shown below. In all graphs, the Control group exhibits normal levels of proteins and gene expression. (Remeber: P > 0.05 means the observed differences are not significant; P < 0.05 means the differences are significant and biologically meaningful).…

Discuss the morphological differences between the parasegments and segments of Drosophila. Discuss the evidence, providing specific examples, that suggests the parasegments of the embryo are the subdivisions for the organization of gene expression.

For each of the following, identify whether the statement about Hox genes is true for Drosophila only, vertebrates only, or both Drosophila and vertebrates. Hox genes are present in the genome. Both Drosophila and vertebrat v Different hox genes are expressed in [Choose ] body segments along the anterior- posterior body axis. Duplication has resulted in several hox [Choose] gene clusters in the genome. Hox genes are expressed after gap [Choose ] genes and pair-rule genes.

Compare and contrast the experimental advantages of Drosophila and C. elegans in the study of developmental genetics.

Developmental genes act hierarchically during pattern formation, first defining broad regions, which aresecondarily refined to form a larger number of smaller regions. Summarize how this general principle isillustrated during the early stages of Drosophila embryogenesis.

Developmental abnormalities can result from: 1. Under expression of some genes 2. All of these choices are correct 3. Inappropriate interaction among gene products that were expressed in the wrong amounts and wrong time 4. Over expression of some genes 5. corrupted timing of the normal time genes are expressed

Discuss how the differential gene expression is possible when all somatic cells carry identical genes and genome.