Biology: The Unity and Diversity of Life (MindTap Course List)
15th Edition
ISBN: 9781337408332
Author: Cecie Starr, Ralph Taggart, Christine Evers, Lisa Starr
Publisher: Cengage Learning
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Chapter 11, Problem 14SQ
Summary Introduction
Introduction: BRCA1 are human genes normally expressed in the cells of breast and other tissue. Actually BRCA is an abbreviation for breast cancer gene. This gene normally plays a big role in preventing breast cancer. They help to repair DNA breaks that can lead to cancer and the uncontrolled growth of tumors.
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Sometimes, malignant cells do not stay properly anchored in tissues because of the loss of function of:
a.
cell walls
b.
oncogenes
c.
plasma membrane adhesion proteins
d.
nuclear membranes
e.
tumor suppressor genes
Match the gene on the left with the gene category on the right.
ERBB2
E-cadherin
BRCA1
Cdk4
A.
oncogene
B.
proto-oncogene
C.
low expression in invasive cells
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tumor suppressor gene
A mutated gene that codes for an altered version of Cdk that is active in the absence of cyclin is a(n) _____. a. kinase inhibitor. b. tumor suppressor gene. c. proto-oncogene. d. oncogene.
Chapter 11 Solutions
Biology: The Unity and Diversity of Life (MindTap Course List)
Ch. 11 - HeLa Cells Are a Genetic Mess HeLa cells can vary...Ch. 11 - HeLa Cells Are a Genetic Mess HeLa cells can vary...Ch. 11 - HeLa Cells Are a Genetic Mess HeLa cells can vary...Ch. 11 - Prob. 1SQCh. 11 - A duplicated chromosome has how many chromatids?Ch. 11 - In the diagrams of the nucleus shown below, fill...Ch. 11 - Homologous chromosomes _______. a. are inherited...Ch. 11 - Most healthy body cells spend the majority of...Ch. 11 - The spindle attaches to chromosomes at the...Ch. 11 - Which is not a stage of mitosis? a. prophase b....
Ch. 11 - In intervals of interphase, G stands for ______....Ch. 11 - Interphase is the part of the cell cycle when...Ch. 11 - After mitosis the chromosome number of a...Ch. 11 - Cytoplasm of a plant cell divides by the process...Ch. 11 - Prob. 12SQCh. 11 - Match each stage with the events listed. _____...Ch. 11 - Prob. 14SQCh. 11 - Prob. 15SQCh. 11 - When a cell reproduces by mitosis and cytoplasmic...Ch. 11 - How is the human life cycle related to the cell...Ch. 11 - The photo on the left shows an early frog embryo...Ch. 11 - The cell above is a lung cell of a salamander. In...Ch. 11 - The eukaryotic cell at left is in the process of...Ch. 11 - Exposure to radioisotopes or other sources of...
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- ________ are changes to the nucleotides in a segment of DNA that codes for a protein. a. Proto-oncogenes b. Tumor suppressor genes c. Gene mutations d. Negative regulatorsarrow_forwardCancer causing genes are called ________. a. transformation genes b. tumor suppressor genes c. oncogenes d. mutated genesarrow_forwardA tumor suppressor gene ___regulates the cell cycle; an example is _____. Select one: a. negatively, cyclin b. positively, retinoblastoma c. positively, p21 d. negatively, retinoblastoma e. positively, RASarrow_forward
- An individual can inherit a gene in which expression has been altered by an ________ change with no mutation of the gene sequence. Choose the description in column 2 that best matches each gene in column 1. p53 c-myc A. tumor suppressor gene B. oncogenearrow_forwardWhich of the following is typical of cancer cells? A. The parent cell of the tumor contains a single mutation in a single checkpoint gene. B. Malignant cells migrate. C. Cancer cells lose the ability to divide. D. Products of oncogenes inhibit mitosis E. Benign tumors invade normal tissue.arrow_forwardPlease help me with the genomics/developmental biology question below: MatchingA. Proto-oncogenesB. Tumor suppressor genes1. _____ Include stimulators of CDK activity2. _____ Hypermethylation of these genes could contribute to tumor formationarrow_forward
- Hypermethylation is thought to contribute to cancer by a. inhibiting DNA replication. b. inhibiting the expression of tumor-suppressor genes. c. stimulating the translation of oncogenes. d. stimulating telomerase.arrow_forwardA gene that codes for a positive cell-cycle regulator is called a(n) _____. a. kinase inhibitor. b. tumor suppressor gene. c. proto-oncogene. d. oncogene.arrow_forwardWhich of the following is not a tumor suppressor gene? a.RET b.RB c.BRCA1 d.BRCA2arrow_forward
- A tumor suppressor gene regulates the cell cycle; an example is . Select one: a. positively, p21 b. negatively, cyclin c. positively, retinoblastoma d. negatively, retinoblastoma e. positively, RAS Cycle HW due Jump to. 4) Next pa cancer stem cellsarrow_forwardTumor Suppressor Genes are often called as gatekeepers because: a. They signify their involvement in governing the dynamics of cell proliferation b. They allow tumors to proliferate at an uncontrolled rate c. To allow a transport channel of suppressors d. They are not referred to as ?gatekeepers?arrow_forwardA tumor suppressor genea. inhibits cell division.b. opposes oncogenes.c. prevents cancer.d. is subject to mutations.e. All of these are correct.arrow_forward
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