Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN: 9781305251052
Author: Michael Cummings
Publisher: Cengage Learning
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Chapter 10.7, Problem 1EG
Summary Introduction
To explain: The way in which a single amino acid in beta globin chain can lead to sickle cell anemia.
Introduction: Sickle cell anemia is a genetic disease that is inherited from one generation to next in an autosomal recessive manner. People suffering from this disease show mutations in the genes that code for the β-globin chain of hemoglobin. This results in the formation of improperly folded hemoglobin molecule. Red blood cells of people suffering from this disease are sickle shaped..
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The T-state of hemoglobin is favored over the R-state in blood under which of the listed conditions?
How many beta globin genes are there?
Name the base change and aminoacid change,responisble for sickle-cell anemmia?
Chapter 10 Solutions
Human Heredity: Principles and Issues (MindTap Course List)
Ch. 10.4 - Prob. 1GRCh. 10.4 - Prob. 2GRCh. 10.7 - Prob. 1EGCh. 10.7 - Prob. 2EGCh. 10 - A couple was referred for genetic counseling...Ch. 10 - A couple was referred for genetic counseling...Ch. 10 - A couple was referred for genetic counseling...Ch. 10 - Many individuals with metabolic diseases are...Ch. 10 - Prob. 2QPCh. 10 - Enzymes have all the following characteristics...
Ch. 10 - Questions 4 through 6 refer to the following...Ch. 10 - Questions 4 through 6 refer to the following...Ch. 10 - Prob. 6QPCh. 10 - Prob. 7QPCh. 10 - Prob. 8QPCh. 10 - a. Compounds A, B, C, and D are known to be...Ch. 10 - b. Compounds A, B, C, and D are known to be...Ch. 10 - a. If an individual who is homozygous for the...Ch. 10 - Prob. 12QPCh. 10 - Suppose that in the formation of phenylalanine...Ch. 10 - If phenylalanine was not an essential amino acid,...Ch. 10 - Phenylketonuria and alkaptonuria are both...Ch. 10 - The normal enzyme required for converting sugars...Ch. 10 - Knowing that individuals who are homozygous for...Ch. 10 - Prob. 18QPCh. 10 - A person was found to have very low levels of...Ch. 10 - If an extra nucleotide is inserted in the first...Ch. 10 - Transcriptional regulators are proteins that bind...Ch. 10 - Prob. 22QPCh. 10 - Prob. 23QP
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- Name the base change and the amino acid change, responsible for sickle cellanaemia.arrow_forwardHow does the pathogenic microorganism mycobacterium tuberculosis secretes lipids called mycolic acids to cause the host macrophage to accumulate cholesterol?arrow_forwardhow do salt bridges that include amino-terminal carbamate stabilize the deoxy form of hemoglobin. Please answer it asap.... With detailed explanation...arrow_forward
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