Human Physiology: An Integrated Approach (8th Edition)
8th Edition
ISBN: 9780134605197
Author: Dee Unglaub Silverthorn
Publisher: PEARSON
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Textbook Question
Chapter 10.1, Problem 4CC
In Figure 10.5, what kind(s) of ion channel might open in neurons A and C that would depress their responsiveness: Na+, K+, Ca2+, or Cl−?
FIG. 10.5 Lateral inhibition
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The action potential is split into 4 parts (A-D).
For each part,
1. Describe what stimulated the channel responsible for this part,
2. what is the likely ion that is moving and
3. explain which direction the ion had to move to create the measured membrane potential.
In the figure to the left, name the 4 phases of the action potential (Note: you have to write in where phase 4 occurs). Describe what happens in each phase with a focus on Na+ and K+ flow through channels and the membrane potential.
Discuss the importance of threshold. How does this relate to the concept of APs being all or none?
The action potential is split into 4 parts (A-D).
For each part,
1. Describe what stimulated the channel responsible for this part,
2. what is the likely ion that is moving and
3. explain which direction the ion had to move to create the measured membrane potential.
+40
B
D
membrane potential (mV)
-40
-60
A
{
2
time (ms)
Chapter 10 Solutions
Human Physiology: An Integrated Approach (8th Edition)
Ch. 10.1 - What advantage do myelinated axons provide?Ch. 10.1 - What accessory role does the outer ear (the pinna)...Ch. 10.1 - Prob. 3CCCh. 10.1 - In Figure 10.5, what kind(s) of ion channel might...Ch. 10.1 - How do sensory receptors communicate the intensity...Ch. 10.1 - Prob. 6CCCh. 10.2 - Prob. 7CCCh. 10.2 - Prob. 8CCCh. 10.2 - Your sense of smell uses phasic receptors. What...Ch. 10.3 - Create a map or diagram of the olfactory pathway...
Ch. 10.3 - Create a map or diagram that starts with a...Ch. 10.3 - Prob. 12CCCh. 10.3 - Are olfactory neurons pseudounipolar, bipolar, or...Ch. 10.3 - Prob. 14CCCh. 10.3 - Prob. 15CCCh. 10.4 - Prob. 16CCCh. 10.4 - Prob. 17CCCh. 10.5 - Prob. 18CCCh. 10.5 - Would a cochlear implant help a person who suffers...Ch. 10.5 - Prob. 20CCCh. 10.5 - Prob. 21CCCh. 10.5 - Prob. 22CCCh. 10.5 - Prob. 23CCCh. 10.6 - What functions do the aqueous humor serve?Ch. 10.6 - Prob. 25CCCh. 10.6 - Prob. 26CCCh. 10.6 - Prob. 27CCCh. 10.6 - Prob. 28CCCh. 10.6 - Prob. 29CCCh. 10.6 - Some vertebrate animals that see well in very low...Ch. 10.6 - Prob. 31CCCh. 10.6 - Macular degeneration is the leading cause of...Ch. 10.6 - Prob. 33CCCh. 10.6 - Draw a map or diagram to explain...Ch. 10 - What is the role of the afferent division of the...Ch. 10 - Prob. 2RQCh. 10 - Prob. 3RQCh. 10 - Prob. 4RQCh. 10 - Prob. 5RQCh. 10 - Prob. 6RQCh. 10 - Prob. 7RQCh. 10 - When a sensory receptor membrane depolarizes (or...Ch. 10 - Prob. 9RQCh. 10 - The organization of sensory regions in the _____...Ch. 10 - Prob. 11RQCh. 10 - Prob. 12RQCh. 10 - Prob. 13RQCh. 10 - Prob. 14RQCh. 10 - Prob. 15RQCh. 10 - Which structure of the inner ear codes sound for...Ch. 10 - Prob. 17RQCh. 10 - Prob. 18RQCh. 10 - Prob. 19RQCh. 10 - Prob. 20RQCh. 10 - Prob. 21RQCh. 10 - Prob. 22RQCh. 10 - Prob. 23RQCh. 10 - Prob. 24RQCh. 10 - Prob. 25RQCh. 10 - Trace the neural pathways involved in olfaction....Ch. 10 - Prob. 27RQCh. 10 - Prob. 28RQCh. 10 - Prob. 29RQCh. 10 - Map the following terms related to vision. Add...Ch. 10 - Prob. 31RQCh. 10 - Prob. 32RQCh. 10 - Prob. 33RQCh. 10 - Prob. 34RQCh. 10 - Prob. 35RQCh. 10 - Consuming alcohol depresses the nervous system and...Ch. 10 - Prob. 37RQCh. 10 - A clinician shines a light into a patients left...Ch. 10 - An optometrist wishes to examine a patients...Ch. 10 - The iris of the eye has two sets of antagonistic...Ch. 10 - As people age, their ability to see at night...Ch. 10 - The relationship between focal length (F) of a...
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- Conformational changes in channel proteins brought about by voltage changes are responsible for opening and closing Na+ and K+ gates during the generation of an action potential. (True or false?)arrow_forwardFigure 35.11 Potassium channel blockers, such as amiodarone and procainamide, which are used to treat abnormal electrical activity in the heart, called cardiac dysrhythmia, impede the movement of K+ through voltage-gated K+ channels. Which part of the action potential would you expect potassium channels to affect?arrow_forwardFigure I shows a schematic of an action potential. How do voltage-gated sodium channels contribute to stages 1, 3 and 6? In your answer, state what happens to the activation and inactivation gates at these three stages. Membrane Potential (mV) 50 -50 -100 -2 t 1 T T 2 3 Time (milliseconds) T 0 1 Figure 1 1 4 51 T T 5 6 7arrow_forward
- Each of the following is a correct relationship between action potential phase and channel status except Select one: O A. hyperpolarizing phase; Na channels open O B. repolarizing phase; K channels open O C. depolarization; Na channels open O D. hyperpolarizing phase; K channels open O E. repolarizing phase; Na channels closedarrow_forwardWhich of the following events correctly ranks steps in an action potential? 1. Voltage-gated sodium and potassium channels transition from closed to open states allowing sodium ions to enter and potassium ions to exit. 2. Voltage-gated sodium channels transition from open to inactivated states. 3. Ligand-gated sodium channels are triggered to open. 4. Peak potassium permeability. 5. Peak sodium permeability. 6. Membranes hyperpolarize due to more potassium ions exiting cell and neuron enters refractory period. 7. Critical threshold is achieved. O 3, 1, 7, 5, 2, 4, 6 O 3, 7, 1, 5, 4, 6, 2 O 3, 4, 1, 2, 6, 7,5 O 6, 7, 3, 2, 5, 4, 1 O 7, 5, 3, 1, 4, 6, 2 4, 6, 3, 7, 5, 2, 1arrow_forwardA membrane potential (Vm) labeled axis on the graph In the graph draw the phases of the action potential Include the channels involved and when they open and close matching them to the Vm Indicate the periods in which the action potential can or cannot occurarrow_forward
- In an experiment, the extracellular [Na+] surrounding a nerve cell was reduced from 145 to 45 mM. Which of the following is the most likely effect of this on action potentials? No action potentials would occur because the concentration of extracellular Na+ is too low. The membrane potential would become more negative so the threshold for action potential generation could not be reached. The nerve cell would still produce an action potential but its amplitude would be reduced and the depolarisation phase would be slower. The nerve cell would still produce an action potential but its amplitude would be reduced and the depolarization phase would be more rapid.arrow_forwardBased upon the changes in permeability seen in the trace below and your knowledge of ion distributions across a cell, predict how ion movements would change during an action potential. Drag and drop each phrase into the appropriate box on the action potential trace. Drag the appropriate labels to their respective targets. Note: not all labels will be used. ►View Available Hint(s) Sodium (Na+) ions move to the axon Sodium (Na) ions move out of the axon Less potassium (K) ions move out of the axon Potassium (K) ions move out of the axon Potassium (K¹) ions move into the axon Sodium (Na) ions stop moving in Membrane potential (mv) +30 +10 0 -10- -30 -50 -70 -90 A PNa 0 PNa 5 6 1 PK Threshold PK 2 Reset Helparrow_forwardWhich protein is responsible for the increase of membrane potential in section 2 potassium leak channels opening of potassium channels opening of ligand gated sodium channels Na+/K+ Atpase opening of sodium channelsarrow_forward
- Consider the following three diagrams of a nerve cell membrane. They show resting potential, depolarization, and hyperpolarization. Figure out which one is which, then draw them in the order they occur in a cell that undergoes an action potential outside + Na* inside K* Na* Nat K Nat K Na potential: -80 mV outside + Na K* Na* inside Na+ K Nat Na* K+ potential: +30 mV outside Na Na Na Na* K+ inside K* Na* Kt potential: -70 mVarrow_forwardWhich of the following phases of an action potential is correctly matched with the changes in ion movement and membrane potential? All of these are correctly matched. Phase 1 – sodium movement into the cell Phase 3 – potassium movement into the cell Phase 2 – sodium movement out of the cellarrow_forwardWhat is the equilibrium potential of chloride for a typical neuron? We will use the following ion concentrations and equilibrium potentials: lon Inside concentration (mM) Outside concentration (mM) Equilibrium Potential Sodium 15 145 +60 mV Potassium 125 5 -85 mV Chloride 13 150 -65 mV 60mV -80mV -90mV -65mVarrow_forward
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