Concept explainers
Case summary:
Mr. Nasheed is diagnosed with cerebral palsy and is suffering from severe skeletal muscle spasms due to cerebral palsy. The drug, dantrolene, prevents the release of Ca2+ from sarcoplasmic reticulum is prescribed to him to manage his muscle spasms.
Characters in the case:
Mr. Nasheed – the cerebral palsy patient.
Adequate information:
Mr. Nasheed is suffering from cerebral palsy. He complains of severe skeletal muscle spasms brought on by his condition. He is prescribed dantrolene, a drug that can prevent the release of Ca2+ from the sarcoplasmic reticulum.
To determine:
The rationale behind using a drug that can prevent the release of Ca2+ from sarcoplasmic reticulum, in the management of skeletal muscle spasms of a cerebral palsy patient.
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Human Anatomy & Physiology (2nd Edition)
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