Genetics: From Genes to Genomes
6th Edition
ISBN: 9781259700903
Author: Leland Hartwell Dr., Michael L. Goldberg Professor Dr., Janice Fischer, Leroy Hood Dr.
Publisher: McGraw-Hill Education
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Textbook Question
Chapter 1, Problem 8P
a. | Are the triplets in the genetic code table shown in Fig. 1.5b written as DNA or RNA? |
b. | Two amino acids are each specified only by a single triplet. Identify these two amino |
acids and the corresponding triplets. | |
c. | If you know the sequence of amino acids in a protein, what does the genetic code |
table allow you to infer about the sequence of base pairs in the gene that specifies | |
that protein? |
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If you know the sequence of amino acids in a protein, what does the genetic code table allow you to infer about the sequence of base pairs in the gene that specifies that protein?
(a) How many activation cycles are needed for a protein with 150 amino acids? (b) How many initiation cycles are needed for a protein with 150 amino acids? (c) How many elongation cycles are needed for a protein with 150 amino acids? (d) How many termination cycles are needed for a protein with 150 amino acids?
a. If a single transition occurs in a codon that specifies Phe, what amino acids can be specified by the mutated sequence? b. If a single transversion occurs in a codon that specifies Phe, what amino acids can be specified by the mutated sequence? c. If a single transition occurs in a codon that specifies Leu, what amino acids can be specified by the mutated sequence? d. If a single transversion occurs in a codon that specifies Leu, what amino acids can be specified by the mutated sequence?
Chapter 1 Solutions
Genetics: From Genes to Genomes
Ch. 1 - Choose the phrase from the right column that best...Ch. 1 - If one strand of a DNA molecule has the base...Ch. 1 - The size of one copy of the human genome is...Ch. 1 - Indicate whether each of the following words or...Ch. 1 - a. How many different DNA strands composed of 100...Ch. 1 - RNA shares with proteins the ability to fold into...Ch. 1 - The human protein lactate dehydrogenase shown in...Ch. 1 - a. Are the triplets in the genetic code table...Ch. 1 - Why do scientists think that all forms of life on...Ch. 1 - Why would a geneticist study a yeast cell or a...
Ch. 1 - How can a scientist tell if a protein present in...Ch. 1 - Figure 1.6 shows the amino acid sequences of parts...Ch. 1 - Why do scientists think that new genes arise by...Ch. 1 - Explain how the exon/intron structure of genes...Ch. 1 - Mutations in genes that change their pattern of...Ch. 1 - A single zebrafish gene function was inactivated...Ch. 1 - Different mutations in the WDR62 gene that...Ch. 1 - Researchers have successfully used gene therapy to...Ch. 1 - By the time this book is published, it will likely...
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- How might a single base substitution in the sequence of a gene affect the amino acid sequence of a protein encoded by the gene, and why? A - It is not possible for a single base substitution to affect protein structure, because each codon is three bases long. B- The amino acid sequence would be substantially altered, because the reading frame would change with a single base substitution. C - Only a single amino acid could change, because the reading frame is unaffected. D- All amino acids following the substitution would be affected, because the reading frame would be shifted.arrow_forwardThe human genome contains thousands of sequences known as small open reading frames, some of which encode proteins of about 30 amino acids. What is the minimum number of nucleotides required to encode such a protein?arrow_forwardBased on the alignment of these protein sequences, which [pairs] of the genes appear to be most similar to each other? And give reasons why?arrow_forward
- What portions of the above genomic sequence actually code for amino acids?arrow_forwardIf the genetic code used 4 bases at a time, how many amino acids could be encoded?arrow_forwardBelow is a sequence of 540 bases from a genome. What information would you use to find the beginnings and ends of open reading frames? How many open reading frames can you find in this sequence? Which open reading frame is likely to represent a protein- coding sequence, and why? Which are probably not functioning protein-coding sequences, and why? Note: for simplicitys sake, analyze only this one strand of the DNA double helix, reading from left to right, so you will only be analyzing three of the six reading frames shown in Figure 19.4.arrow_forward
- If proteins were composed of only 12 different kinds of aminoacids, what would be the smallest possible codon size in a geneticsystem with four different nucleotides?How is the answer 2?arrow_forwardAssuming the genetic code is a triplet, what effect would the addition or loss of two nucleotides have on the reading frame? The addition or loss of three, six, or nine nucleotides?arrow_forward. While studying the structure of a small gene that was recently sequenced during the Human Genome Project, an investigator notices that one strand of the DNA molecule contains the following: 20 adenine (A) bases 30 cytosine (C) bases25 guanine (G) bases 22 thymine (T) bases How many of each base is found in the complete double-stranded molecule?arrow_forward
- Hơ many mismatches would you expect to find between this sequence and the reference sequence? I know the answer is 3, can you please explain why?arrow_forwardAssume that an error is made: adenine and guanine are matched as base pairs. What would be the impact on the structure of DNA? What would be the structural impact if adenine and cytosine were paired?arrow_forwardA scientist wants to create a new enzyme for the synthesis of a new smallmolecule that will be used in the treatment of lung cancer. The scientist wants to use a technique that allows to shuffle protein domains. Protein A and Protein B are 5 and 7 different domains respectively. If 3 domains from A and 4 domains fromB are chosen and paired. 1- How many possible arrangements are present? 2-How many primers are needed to amplify domain sequences to prepare all constructs?arrow_forward
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