Genetics: From Genes to Genomes
6th Edition
ISBN: 9781259700903
Author: Leland Hartwell Dr., Michael L. Goldberg Professor Dr., Janice Fischer, Leroy Hood Dr.
Publisher: McGraw-Hill Education
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Textbook Question
Chapter 1, Problem 16P
A single zebrafish gene function was inactivated completely by mutation, and a zebrafish with this mutation had none of its normal horizontal stripes. For each of the following statements, indicate whether the statement is certainly true, certainly untrue, or if there is insufficient information to decide.
a. | The normal gene function is required for the viability of the zebrafish. |
b. | The normal gene function is required for the formation of stripes. |
c. | The normal gene function is required to make the pigment deposited in the stripes. |
d. | The gene is required in zebrafish only for stripe formation. |
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A single zebrafish gene function was inactivated completely by mutation, and a zebrafish with this mutation had none of its normal horizontal stripes. Foreach of the following statements, indicate whether the statement is certainly true, certainly untrue, or if thereis insufficient information to decide.a. The normal gene function is required for the viability of the zebrafish.b. The normal gene function is required for the formation of stripes.c. The normal gene function is required to make thepigment deposited in the stripes.d. The gene is required in zebrafish only for stripeformation.
Most organisms display a circadian rhythm, a cycling of biological processes that is roughly synchronized with day length. In Drosophila, pupae eclose (emerge as adults after metamorphosis) at dawn.
a)Using this knowledge how would screen for Drosophila mutants that have an impaired circadian rhythm?
b)In each case, how would you clone the genes you identified by mutation?
The functions of almost all of the genes in the lambda genome were first explored using mutations. What do you think the mutant phenotype would be if you made an inactivating mutation in the c gene, and why? Be very specific but also very brief.
Chapter 1 Solutions
Genetics: From Genes to Genomes
Ch. 1 - Choose the phrase from the right column that best...Ch. 1 - If one strand of a DNA molecule has the base...Ch. 1 - The size of one copy of the human genome is...Ch. 1 - Indicate whether each of the following words or...Ch. 1 - a. How many different DNA strands composed of 100...Ch. 1 - RNA shares with proteins the ability to fold into...Ch. 1 - The human protein lactate dehydrogenase shown in...Ch. 1 - a. Are the triplets in the genetic code table...Ch. 1 - Why do scientists think that all forms of life on...Ch. 1 - Why would a geneticist study a yeast cell or a...
Ch. 1 - How can a scientist tell if a protein present in...Ch. 1 - Figure 1.6 shows the amino acid sequences of parts...Ch. 1 - Why do scientists think that new genes arise by...Ch. 1 - Explain how the exon/intron structure of genes...Ch. 1 - Mutations in genes that change their pattern of...Ch. 1 - A single zebrafish gene function was inactivated...Ch. 1 - Different mutations in the WDR62 gene that...Ch. 1 - Researchers have successfully used gene therapy to...Ch. 1 - By the time this book is published, it will likely...
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