Genetics: From Genes to Genomes
6th Edition
ISBN: 9781259700903
Author: Leland Hartwell Dr., Michael L. Goldberg Professor Dr., Janice Fischer, Leroy Hood Dr.
Publisher: McGraw-Hill Education
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Textbook Question
Chapter 1, Problem 3P
The size of one copy of the human genome is approximately 3 billion base pairs, and it contains about 27,000 genes organized into 23 chromosomes.
a. | Human chromosomes vary in size. What would you predict is the size of the |
average chromosome? | |
b. | Assuming that genes are spread evenly among chromosomes, how many genes |
does an average human chromosome contain? | |
c. | About half of the DNA in chromosome contains genes. How large (in base pairs) |
is an average human gene? |
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Chapter 1 Solutions
Genetics: From Genes to Genomes
Ch. 1 - Choose the phrase from the right column that best...Ch. 1 - If one strand of a DNA molecule has the base...Ch. 1 - The size of one copy of the human genome is...Ch. 1 - Indicate whether each of the following words or...Ch. 1 - a. How many different DNA strands composed of 100...Ch. 1 - RNA shares with proteins the ability to fold into...Ch. 1 - The human protein lactate dehydrogenase shown in...Ch. 1 - a. Are the triplets in the genetic code table...Ch. 1 - Why do scientists think that all forms of life on...Ch. 1 - Why would a geneticist study a yeast cell or a...
Ch. 1 - How can a scientist tell if a protein present in...Ch. 1 - Figure 1.6 shows the amino acid sequences of parts...Ch. 1 - Why do scientists think that new genes arise by...Ch. 1 - Explain how the exon/intron structure of genes...Ch. 1 - Mutations in genes that change their pattern of...Ch. 1 - A single zebrafish gene function was inactivated...Ch. 1 - Different mutations in the WDR62 gene that...Ch. 1 - Researchers have successfully used gene therapy to...Ch. 1 - By the time this book is published, it will likely...
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- Each cell of the human body contains 46 chromosomes. How many DNA molecules does this statement represent? How many different types of DNA molecules does it represent?arrow_forwardThe size of the human genome is 3.3 Giga bases (Gb). If stretched and aligned head-to-tail, it would correspond to a DNA length of 1.122 metres. Considering that the genome of Drosophila is 120x10^6 bp, how many meters of DNA are packed in a Drosophiladiploid cell? a. 0.041 b. 0.082 c. 0.816 d. 1.200arrow_forwardWhat is a centromere? How does the position of centromere form the basis of classification of chromosomes. Support your answer with a diagram showing the position of centromere on different types of chromosomes.arrow_forward
- Hypothetically, a cell has DNA that weighs 10 picograms. This cell goes through S phase and is about to undergo mitosis. How much does the DNA of this cell weight now? How much would the DNA of the two cells produced at the end of mitosis weigh? Explain your reasoning.arrow_forwardExplain how a genetic map (in map units) is related to actual physical distance (in base pairs of DNA)?arrow_forwardAs pointed out in the text, you and a complete stranger are 99.9% identical in DNA sequence. But you also differ at more than 3 million base pairs. Is this a large or a small difference? What are some of the consequences of these similarities and differences?arrow_forward
- (a) Explain the relationship between DNA, genes, and chromosomes during the passing of genetic information. (b) During the passing of genetic information from one generation to the next via chromosomes, nondisjunction can occur, interrupting the process. Describe the events that take place during nondisjunction.arrow_forwardA form of male sterility in corn is inherited maternally. Marcus Rhoades first described this cytoplasmic male sterility by crossing female gametes froma male sterile plant with pollen from a male fertileplant. The resulting progeny plants were malesterile.a. Diagram the cross, using different colors andshapes to distinguish between nuclear (lines) andcytoplasmic (circles) genomes from the male sterile (one color) and male fertile (another color)strains.b. Female gametes from the male sterile progenywere backcrossed with pollen from the same malefertile parent of the first cross. The process was repeated many times. Diagram the next two generations including possible crossover events.c. What was the purpose of the series of backcrosses?[Hint: Look at your answer to part (b) and thinkabout what is happening to the nuclear genome.]Why could Rhoades interpret these results as ademonstration of cytoplasmic male sterility?arrow_forwardA scientist investigating the genome of two related individuals observes a difference of a few nucleotides in one individual compared to the other. The nucleotide differences are in a region of noncoding DNA on chromosome 1. Would these differences be considered a mutation? Why or why not? Yes, the difference in nucleotide sequences between the individuals is a mutation because it will affect the phenotype of the two individuals. Yes, any heritable variation in the nucleotide sequence is considered a mutation, even if that variation is in a noncoding region of DNA. Not enough information was provided to determine if this nucleotide difference is a mutation because the effect on phenotype is unknown. No, the change in nucleotide sequence doesn't appear in a coding region of the DNA and so can't be a mutation.arrow_forward
- What percentage of the DNA in the genome actually corresponds to genes? How much is actually protein-coding exons? What makes up the rest?arrow_forwardSuppose that you could undergo genetic testing at age 18 for susceptibility to a genetic disease that would not appear until middle age and has no available treatment. a. What would be some of the possible reasons for having such a genetic test and some of the possible reasons for not having the test? b. Would you personally want to be tested? Explain your reasoning.arrow_forwardFor each of the following, decide if it could be appropriatelydescribed as a genome:A. The E. coli chromosomeB. Human chromosome 11C. A complete set of 10 chromosomes in cornD. A copy of the single-stranded RNA packaged into humanimmunodeficiency virus (HIV)arrow_forward
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