You just received the properly labeled blood bank specimen on patient Aran Stark. You decide to collect some background information about her known historical antibodies before beginning the work-up knowing that she has a history of anti-E, anti-K, anti-Jk^a, anti-Fy^a, anti-M and anti-Le^a. Which antibody can be neutralized?

Basic Clinical Laboratory Techniques 6E
6th Edition
ISBN:9781133893943
Author:ESTRIDGE
Publisher:ESTRIDGE
Chapter4: Basic Immunology And Immunohematology
Section4.6: Abo Grouping
Problem 7RQ
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You just received the properly labeled blood bank specimen on patient Aran Stark. You decide to collect some background information about her known historical antibodies before beginning the work-up knowing that she has a history of anti-E, anti-K, anti-Jk^a, anti-Fy^a, anti-M and anti-Le^a.

Which antibody can be neutralized? 

Which antibody is destroyed with 0.2M DTT treatment?

Which antibody reactivity is enhanced by acidification? 

Which of the antibodies that are typically IgG in nature are destroyed by enzymes?

Which are enhanced by enzymes? 
 
Which of these antibodies have been known to cause hemolytic transfusion reaction?
 
Which of these antibodies are known to react at room temperature?
 
Which of these antibodies react best at 37C? *
 
When you complete the work-up, you note that the anti-Jk^a antibody is no longer detectable. Can the patient receive red blood cells that contain the Jk^a antigen? Why or why not?
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