When a patient goes from testing negative for a specific antibody to testing positive a month later for the same antibody, they may have a false negative immunocompetence seroconversion
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When a patient goes from testing negative for a specific antibody to testing positive a month later for the same antibody, they may have
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- the immunohematology test that is incubated after collection isa- Group and Rhb- Cross matchc- Coomb’s Directd- Cold Agglutininse- Coomb’s Indirectasap Which of the following would not be consistent with Infectious Mononucleosis (IM): a Absolute Lymphocyte count of <4.0 x 109/L b Relative Lymphocyte count usually >50% c Greater than 20% reactive lymphocytes counted on manual differential d Positive heterophile antibody test.When a patient exhibits a four-fold or greater rise in antibody titer against a specific microbial antigen between acute-phase and convalescent-phase serum samples, this is considered to be a "seroconversion". Which of the following would be a correct interpretation of a seroconversion? None of the other four answers are a correct interpretation of a seroconversion These findings cannot be interpreted because antibodies aren't specific enough for antigens There is no evidence of current active infection because that would require that the antibody titer is decreasing rather than increasing These results show that the microbe itself has been detected in the patient's sample(s) The results show evidence of current or recent infection by the specific microbe because there has been an active immunologic response to its antigen
- Antibodies designed to interact with a specific antigensite are (monoclonal, polyclonal).Match the following term with its description or definition. Immunoglobulin domain Amino acids that are separated in the protein chain but come together in the folded protein Antigen that carries several epitopes of the same or different specificity Heavy chain classes Soluble proteins that carry only one copy of the epitope ✓ Choose... IgG, IgM, IgD, IgA, IgE Multivalent antigen Discontinuous epitope Monovalent antigen Repeated barrel-shaped structure Choose...If I have been exposed to an infectious microbe for the second time, which of the following antibodies will be release in the greatest amount? ОООС IgE IgM IgG IgA
- The greatest concentration of antibodies is found in the fraction of the serumA lab tech was rushed to the ER after a needlestick injury due to improper needle disposal. A Hepatitis Panel was ordered and the results were as follows: A Hepatitis Panel was ordered, and the results were as follows:HBsAg: negativeAnti- HBc (IgM): negativeAnti-HBc: negativeAnti-HBs: positiveAnti-HCV: negative Question: Why were HAV antibodies not tested for?A 16 year old girl without past medical history presented to her GP after returning from a holiday at the beach. She had developed a red rash on her cheeks and over the bridgeof her nose. She was referred on to the children's hospital and mentioned that when she woke up in the morning her finger joints and hips were stiff. A blood test was done to test for anti-nuclear antibodies. This was positive to a titre of 1:1280. Lymph nodes behind her ears and in her neck were enlarged. She was advised to avoid direct sunlight and to take an anti- malarial agent (hydroxycholorogquine). Interpret the results and explain the possible diagnosis for this patient.