Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN: 9780134580999
Author: Elaine N. Marieb, Katja N. Hoehn
Publisher: PEARSON
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You are studying the enzyme kinetics of enzymes in the TCA cycle. You add a molecule to the mixture that appears to act as a competitive inhibitor of one of the enzymes. At first, you cannot tell which enzyme is inhibited, but you can tell that it is bound to the inner mitochondrial membrane. Can you guess which TCA enzyme you have inhibited and how do you know? Where are other enzymes located in the mitochondrion?
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- You treat cells with 2,4 dinitrophenol (DNP). This compound creates a temporary channel in the inner membrane of the mitochondria though the protons can move. Which of the following would you observe in these cells? Select all that apply The cells do not synthesize ATP in the presence of DNP The cells synthesize ATP in the presence of DNP The cells reduce oxygen in the presence of DNP The cells generate carbon dioxide in the presence of DNParrow_forwardDuring aerobic respiration, in the mitochondria of animal cells, when diatomic oxygen molecules (O2) are consumed, to which of the following product molecules are these oxygen atoms going? to C6H12O6, O2, and H2O only to C6H12O6 only to CO2 and C6H12O6 only to H2O only to C6H12O6 and O2, onlyarrow_forwardYou are given a suspension of purified mitochondria that are known to have adequate reserves of NAD+, FAD, and ADP/inorganic phosphate. Assume that the mitochondrial preparation you are working with is free of cytosolic components (enzymes and metabolites) and assume that all the compounds listed below can cross both mitochondrial membranes, When glucose is added to this suspension: a. What is the effect on oxygen consumption by the purified mitochondria? b. Explain your answer above. When citrate is added to this suspension: c. What is the effect on oxygen consumption by the purified mitochondria? d. Explain your answer above.arrow_forward
- To learn more about the role of the electron transport chain in generating energy during respiration in this organism, you use two drugs. These drugs can each pick up electrons from specific intermediates in the pathway as shown above. You treat cells carrying out respiration with either a saturating dose of drug A or B, so that all the electrons which would normally continue along the pathway are captured by the drug in question. Complete the following table. In the presence of drug A, will the cells continue to consume O2? (yes or no), will the cells continue to produce CO2? (yes or no) In the presence of drug B, will the cells continue to consume O2? (yes or no), will the cells continue to produce CO2? (yes or no)arrow_forwardADP and inorganic phosphate are provided for oxidative phosphorylation via an: ADP-ATP antiport and a proton-phosphate symport in the inner mitochondrial membrane. ADP-ATP antiport and a proton-phosphate symport in the outer mitochondrial membrane. O ADP-ATP antiport in the inner mitochondrial membrane and a phosphate uniport in the mitochondrial intermembrane space. ADP-phosphate symport in the inner mitochondrial membrane.arrow_forwardTransporting anything through the mitochondrial membrane can be difficult. How do cells get Oxaloacetate in and out?arrow_forward
- a protein cluster, found in the inner membrane of mitochondria that uses the energy of a hydrogen ion concentration gradient to make ADP from ATP is called what?arrow_forwardWhich of the following statements about cellular respiration is TRUE in eukaryotes? A. For every molecule of NADH oxidized in the electron transport chain, 1 molecule of ATP is produced. B. ATP synthase harnesses the flow of protons (hydrogen ions = H+) from the mitochondrial matrix to the intermembrane space to produce ATP. C. ATP synthase transduces the flow of protons (hydrogen ions = H+) from the intermembrane space to the mitochondrial matrix into kinetic (mechanical) energy D. H2O is the final electron acceptor in the electron transport chain, being oxidized to O2 and H+. E. All of the above are truearrow_forwardEnergy is required for which of the following? Choose one from the following: (A) movement of hydrogen ions from the outer matrix to the inner matrix of the mitochondrion (B) movement of hydrogen ions from the inner matrix to the outer matrix of the mitochondrion (C) both A and B require energy (D) neither A nor B require energyarrow_forward
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