With regard to cancer cells, which of the following statementsare true?A. Cancer cells are clonal, which means they are derived from asingle mutant cell.B. To become cancerous, cells usually accumulate multiplegenetic changes that eventually result in uncontrolledgrowth.C. Most cancers are caused by oncogenic viruses.D. Cancer cells have lost the ability to properly regulate celldivision.

Which of the following types of mutations would be advantageous to a cancer cell (select all that apply)?   A. An inactivating mutation in a tumor suppressor gene   B. Methylation of the promoter of a tumor suppressor gene   C. An inactivating mutation in an oncogene   D. Mutation that inactivated DNA repair gene   E. An inactivating mutation in an oncogene

P53 is a tumor suppressor protein.   The protein is present in the cell at all times but is activated by protein kinases that are, in turned activated by DNA damage.  What would be the result of a mutation of the P 53 gene in cell that resulted in a form of P53 that was permanently active? Group of answer choices A. the cell cycle would be inhibited in all cells in a tumor if it forms B. the cell cycle would be inhibited C. the cell would form a tumor D. the cell has a higher probability of forming a tumor E. the cell cycle of all cells in the body would be inhibited

ge Which of the following would most likely promote necrosis? Select one: a. activation of p53 b. pathogenic infection c. cyclin d. activation of cdk e. inactivation of p53 Cycle HW due Jump to... 46 Next page cancer stem cells

Which of the following are characteristics of aging cells (select all that apply)? A. Chronic inflammation results in premature shortening of telomeres B. Lengthening of telomeric DNA sequence C. Accumulation of telomere-dysfunction–induced foci (TIFs) D. Older cells produce more telomerase E. Increased erosion of telomeres

When cancer cells metastasize, they: a. b. ○ c. travel to distant and different body parts to begin new tumors. stay in their place of origin to destroy adjacent tissues. are not able to invade blood vessels.

If two mutational events are sufficient to cause some forms of cancer, what distinguishes familial forms (i.e. those that "run in families") of cancer from spontaneous cases?   A. spontaneous forms inherit both mutations   B. familial forms are caused by chance alone   C. familial forms inherit one mutation   D. there is no difference   E. none of the above

With regard to human cancer cells, which of the following statements is true? A. Cancer cells within one tumor usually do not share common mutations B. Cancer cells generally have lost the ability to divide C. Oncogenes are non-human genes not related to normal genes in the human genome  D. Mutations in DNA repair genes result in an increased chance of getting cancer.

You have treated undifferentiated embryonic stem cells (ESCs) with sonic hedgehog (Shh)for several days. This should induce a neural fate in your ESCs and you hope that you havebeen successful in differentiating the ESCs into NSCs. What is one assay you could use to testwhether your cells had differentiated into NSC-like cells? Name and shortly describe the assay?

A tumor suppressor gene ___regulates the cell cycle; an example is _____. Select one: a. negatively, cyclin b. positively, retinoblastoma c. positively, p21 d. negatively, retinoblastoma e. positively, RAS