Which of these events do you think is likely to promote tumorigenesis in affected cells? Group of answer choices DNA methylation of the promoter region of a tumor suppressor gene Hypermethylation of transcription factors that antagonize Wntsignaling Open chromatin in the region of of DNA harboring an activating mutation of beta-catenin All of these

Q: for question 1, choose wheater each choice is either tumor suppressor or proto oncogene\ for…

A: Proto-oncogenes and tumor suppressor genes are two types of genes that play important roles in the…

Q: 25 of 41 The products of tumor suppressor genes cell division; the products of oncogenes cell…

A: Tumour Suppressor Gene:  A tumour suppressor gene is a type of gene that helps control cell…

Q: The protein p53 is activated when the cell's DNA is damaged. p53 helps to arrest the cell cycle in…

A: Cell division is controlled by a protein that is encoded by a tumor suppressor gene. Uncontrolled…

Q: 24 of 41 The products of tumor suppressor genes cell division; the products of oncogenes cell…

A: Normal genes that slow cell division, fix DNA errors, or warn cells when to die are known as tumour…

Q: Which of the following is the best example of a tumor promoter? A chemical that allows cells to…

A: Answer : Option B- a chemical that activates mTOR.  Tumour promotors are agents or chemicals that…

Q: Cancer is a complex respo canc comprises mar diseases with a comme tagens as well as very little…

A: Cancer is a disease that occurs when cells in our body show abnormal and uncontrolled growth. These…

Q: Cisplatin is an anticancer drug that exerts its effects by creating DNA adducts and damaging DNA.…

A: Cisplatin is a well-known anticancer drug widely used in the treatment of various malignancies,…

Q: Which of the following is NOT accurate? The gain of function mutation of just one copy of a tumor…

A: Tumour suppressor genes are the ones that inhibit cell survival and proliferation—these genes code…

Q: Given the following scenario, indicate if this will ‘promote’ or ‘prevent’ cancer development: An…

A: Bcl-2, or B-cell lymphoma 2, is a protein that plays a crucial role in regulating apoptosis…

Q: What causes cancer (think mutations, repair mechanisms, dna polymerase, symmatic/ germ line, genes +…

A: Cancer can be defined as a disorder in which there is abnormal and uncontrolled proliferation of the…

Q: The Bax gene, codes for a cytosolic protein that plays an important role in apoptosis. Growth factor…

A: Bax gene Bcl-2-associated X protein which is pro-apoptotic member of the Bcl-2 gene family. Cell…

Q: Which of the following mutations is likely to be associated with development of cancer? Loss of SMO…

A: The cells are basic structural and functional units of life. The human body contains many types of…

Q: The mutation of which of the following proto-oncogenes can lead to an increased susceptability to…

A: Introduction:- Cancer or malignancy is defined as the uncontrolled and unregulated proliferation of…

Q: Which of the following do cancer cells rely on to be able to divide indefinitely? tumor suppressors…

A: Cancer is defined as the biological disorder in which the cells undergo uncontrolled growth and cell…

Q: After cutting yourself with a knife while chopping vegetables, your body begins extensive mitosis…

A: The given DNA sequence is as follows,  TAC GGG CAA ACC TCT AGC CCA ATG TCG ATC

Q: 1. For each of the following genes, categorize them as a tumor suppressor gene or a protooncogene.…

A: Bcl-2 gene is a protooncogene.The Bcl-2 can act as a barrier to apoptosis and and facilitate the…

Q: Although tobacco smoking is responsible for a large number of human cancers, not all smokers develop…

A: Cancer refers to the uncontrolled cell division caused by the mutations in the genes which control…

Q: You are studying cancer progression in mice. Your results show the following pathway in which two…

A: From the given data the observations made are: The experiment is conducted in a nutrient-enriched…

Q: Determine if the gene on the left is a proto-oncogene or tumor suppressor. APC p53 Ras [Choose]…

A: Proto oncogene These are genes that are involved in normal cell growth. Mutations in these genes may…

Q: Cell division is carefully regulated and coordinated in eukaryotic cells by protein kinases that…

A: The division of all cells must be carefully regulated and coordinated with both cell growth and DNA…

Q: The normal copies of tumor-suppressor genes encode proteins that have which three types of…

A: A tumour suppressor gene also known as anti-oncogene is a gene that is responsible to regulate the…

Q: Protein P, normally stimulates apoptosis or cell death when activated. Consider a cell with a…

A: The construction of this question gives us an  information about the nature of protein P, P when…

Q: Cancer often results from a multistage process involving an initiating event (mediated by a viral…

A: Phorbol esters are a group of chemicals that are found in many plants. They are the ester…

Q: You are looking at the results of a western blot from the lysates of cells harvested from a…

A: When you observe an increased expression of INK4-p16 in the lysates of cells harvested from a…

Q: Which of the following usually has a function dealing with inspecting newly replicated DNA for…

A: DNA replication is a process that occurs in all living organisms. In this process, DNA strands of…

Q: Why is the p53-meditated apoptosis pathway, and the GSK3 signaling pathway important for cancer…

A: p53 is a critical tumour suppressor that is mutated in ~50% of human cancers. Inunstressed cells p53…

Q: The belief that rare mutations within a single cell allow it bypass growth barriers to become…

A: Driver Mutations: These are genetic changes that directly drive growth to cells, allowing them to…

Q: In a patient with a constitutively active receptor tyrosine kinase that increases the activity of…

A: Tyrosine kinase is a type of enzyme that plays a crucial role in cell signaling pathways by adding a…

Q: An experiment is carried out as depicted in Figure 1. Two drugs, staurosporine and camptothecin, are…

A: When the normal cells divide uncontrollable or abnormally due to some mutations, then it may lead to…

Q: In some cancer cells, a specific gene has been duplicated many times. Is this gene likely to be an…

A: Cancer is an uncontrolled division of cell that has a defunct apoptosis mechanism. Usually, when…

Q: p53 is an important DNA damage checkpoint protein that stops the transition to S phase and is lost…

A: p53, also known as TP53 or tumor protein (EC :2.7. 1.37) is a gene that codes for a protein that…

Q: Explain why p53 is mutated in the vast majority of human cancers.

A: Any isoform of a protein encoded by homologous genes in multiple animals, such as TP53 and Trp53, is…

Q: g protein D. Growth factor receptor ng Tool 0 Q ing C. Growth factor-binding protein D. Growth…

A: The question is asking about the type of protein produced by the Rb gene, which is located at the…

Q: Why would a mutation in BRCA1 be considered a driver mutation?  b. Based on what you’ve learned…

A: In this question, we  have to answer 'BRCA gene consider as driver mutation and ATM consider as a…

Q: The palladin gene, which plays a role in pancreatic cancer (see theintroduction to this chapter), is…

A: A disease is an abnormal condition that negatively impacts the structure and function of an…

Q: Discuss the relationship between protooncogenes and tumor suppressor genes and cancer. ( no intro…

A: Cancer is a disease in which some of the body's cells grow uncontrollably and spread to other parts…

Q: All but which of the following best explains the advantage of cancer cells expressing PKM2 over…

A: Cancer refers to abnormal growth of the cells and this they will divide uncontrollably. The cancer…

Q: Which one of the following events is unlikely to beassociated with cancer?a. mutation of a cellular…

A: Cancer is basically the uncontrolled proliferation of abnormal or mutated cells in the body. It is…

Q: The P63 and P53 have similar functionalities in the cell, however, p53 is rarely associated directly…

A: Tumor protein 63 (p63) could also be a transcription factor of the p53 gene family encoded by the…

Q: Explain the concept of loss of heterozygosity (LOH). Why do most cancer cells exhibit LOH of one or…

A: The loss or inactivation of a normal allele in a normal or somatic cell is a requirement for cancer…

Q: Which type of mutation would NOT be involved in the inactivation of a tumor suppressor gene?

A: Normal cell growth in body is controlled by -  1. Protooncogene or cellular oncogene - Protooncogene…