Which of the following is true about cystic fibrosis (CF) and the CFTR transporter protein? CFTR is a member of the ABC superfamily of membrane pumps which pumps chloride ions into the cells O None of the other are true O CFTR mutations result in a mutated protein, which pumps too many chloride ions out of the cell O CFTR mutations result in a mutated protein, which blocks sodium ion movement from inside the cell to outside the cell The normal CFTR channel protein is a chloride uniporter, but CF patients have a mutation that makes it require ATP

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Which of the following is true about cystic
fibrosis (CF) and the CFTR transporter
protein?
O CFTR is a member of the ABC superfamily
of membrane pumps which pumps chloride
ions into the cells
None of the other are true
O CFTR mutations result in a mutated protein,
which pumps too many chloride ions out of
the cell
O CFTR mutations result in a mutated protein,
which blocks sodium ion movement from
inside the cell to outside the cell
The normal CFTR channel protein is a
chloride uniporter, but CF patients have a
mutation that makes it require ATP
Transcribed Image Text:Which of the following is true about cystic fibrosis (CF) and the CFTR transporter protein? O CFTR is a member of the ABC superfamily of membrane pumps which pumps chloride ions into the cells None of the other are true O CFTR mutations result in a mutated protein, which pumps too many chloride ions out of the cell O CFTR mutations result in a mutated protein, which blocks sodium ion movement from inside the cell to outside the cell The normal CFTR channel protein is a chloride uniporter, but CF patients have a mutation that makes it require ATP
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