Which of the following is true about cystic fibrosis (CF) and the CFTR transporter protein? CFTR is a member of the ABC superfamily of membrane pumps which pumps chloride ions into the cells O None of the other are true O CFTR mutations result in a mutated protein, which pumps too many chloride ions out of the cell O CFTR mutations result in a mutated protein, which blocks sodium ion movement from inside the cell to outside the cell The normal CFTR channel protein is a chloride uniporter, but CF patients have a mutation that makes it require ATP

The diagram below shows three different proteins embedded in a cell membrane, as well as the concentration gradient surrounding the cell high concentration channel protein carrier protein lipid bilayer 1 21 3 low concentration Which of the following statements correctly states the process shown in the diagram? O The process labeled 1 shows how cells can easily move molecules with the concentration gradient using high energy molecules. The process labeled 2 shows how cells move molecules against the co entration gradient without needing hic energy molecules The process labeled 3 shows how cells use energy to facilitate the active transport of molecules against the concentration gradient All three processes show how molecules freely move in and out of the cell regardless of the concentration gradient or available en Previous

You have made several mutations in the coding region of the gene coding for the sodium channel and placed them in expression vectors to have the synthetic proteins placed in the membranes of the cultured cells. As a result, the cells no longer contract with the same force as the wild type.  why does this occur?

The binding of sodium ions (Na+) to a membrane protein is one of the first steps in initiation of the sodium-potassium pump that moves these ions across the membrane. The picture shows the inital set up in this process. How does the protein get the energy needed to continue the process of moving the (Na+) across the cell membrane? Membrane Protein ONa+ Inside the Cell A. O O Nat oc Outside the Cell Con Mitochondria will attach to the protein and provide the energy to push the Na+ through the protein. Energy from ADP is released and a channel in the membrane protein permanently B. opens, resulting in the passage of the Nat. Energy produced from the difference in solute concentration on both sides of the O c. membrane pulls the Na+ through the protein. Con с ATP attaches to the protein and releases a phosphate, making energy available to OD. change the shape of the protein and allowing the passage of the Nat.

If GTP hydrolysis occurs on a tubulin molecule at the plus end of a microtubule protofilament before another tubulin molecule is added, what typically happens? the GDP is rapidly exchanged for a fresh molecule of GTP the microtubule depolymerizes the microtubule polymerizes the microtubule is stabilized the protofilaments assemble into a hollow tube

The Na+/glucose cotransporter in ION-GRADIENT-DRIVEN ACTIVE TRANSPORT, against its gradient. Na+/glucose Na+/K+ glucose/glucose Na+/Na+ moves down its gradient and

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Which of the following small GTP-binding proteins does NOT play a role in cell migration during chemotaxis? O Cap Z Rho Cdc42 O All of the listed GTPases play a role in cell migration O Rac ◆ Previous

A pharmaceutical company just developed a drug (Cytarabine) that inhibits the activity of cytosine deaminase but increases intracellular concentrations of ara-dCTP in tumor cell. This will likely produced increased tumor sensitivity to Cytarabine. Group of answer choices True False

If a skeletal muscle has depleted its stores of ATP how will the altered transport properties of the following transporters affect cytosolic ion concentrations (increase, decrease, no change) relative to normal?   Skeletal Muscle Cell With Depleted ATP Stores Ion transporter Cytosolic K+ Cytosolic Na+ Cytosolic Ca2+ NKA         NCX         SERCA