Which of the following interpretations for the missing hereditary are reasonable? 1. The reported high hereditary may have been over estimated by family studies 2. Genetic interaction and gene environment interactions are not easily captured 3. The variations with large effects are usually rare

5. solve and discuss genetics problems illustrating the different types of gene interactions, interpret results and infer relationships related to dominance, sex linkage, recombination etc

Until very recently, the fitness of an individual getting familial retinoblastoma was zero, and if the frequency of babies with the inherited disease is 1/20000, what is the best estimate of the mutation rate of the wild type allele to the non-functional form?

ols Add-ons Help Last edit was seconds ago Calibri 11 В I U A 2 5 6 I 7 16. The characteristic of albinism (lack of pigment in skin and hair), can be caused by a single gene. The following pedigree shows a family in which some people are affected by albinism. 4 6 8 II 4 IV 1 3 4 5 6 7 a. Using just the information on this pedigree, is albinism caused by a dominant allele or recessive alleles? b. What are the genotypes of the great-grandparents (generation I)? hp

How can you recognize codominance?   Group of answer choices 1. The heterozygote expresses the phenotypes coded for by both alleles 2. The phenotype of the heterozygote is intermediate between the 3. phenotypes of the homozygotes. 4. The alleles affect more than one trait. 5. The trait exhibits continuous variation

Which of the following statements about the pedigree shown below is FALSE? 2 II 3 II 2 3 4 The phenotype of individual II-3 is affected. The genotype of individual Il-1 could be Aa or AA. Genotype of individual Il-3 is AA. Genotype of individual Il-2 is aa. 2.

Please help with the following: How does penetrance differ from expressivity in genetics? A. Penetrance is the percentage of individuals with a specific genotype that exhibit the expected phenotype while expressivity is the degree to which a phenotypic character is expressed. B. Penetrance is the degree of lethality of a specific genotype while expressivity is how frequently that genotype is seen in the population. C. Penetrance is the presence of more than two alleles at a locus within a group of individuals while expressivity is the influence of sex on which alleles express themselves. D. None of the above. E. Penetrance refers to the paternal effects of a gene while expressivity refers to the maternal effects of a gene.

10. Record the class data for these traits. Color vision Red-green color blind Widow's peak No widow's peak Trait Widow's peak Free earlobes Mid-digit hair Widow's peak # of WW people # of Ww people q² # of ww people Class data 11. As before, use the Hardy-Weinberg equations to estimate how many people in our classroom population have a given genotype. We will skip this for red-green color blindness because X-linked traits require more complicated calculations. 15 6 9 9 Р Free earlobes Attached earlobes Mid-digit hair No mid-digit hair # of EE people # of Ee people # of ee people p² Free earlobes Class data 6 2pq 9 lo 5 Does p²+2pq+q² = 1? Mid-digit hair E # of HH people # of Hh people # of hh people 12. In our class, is the dominant trait always the most frequent? Why do you think this is? 13. Do you think the frequency of these traits will change if we repeat this experiment in 30 years? (Some food for thought: Do these traits provide an advantage to survival? Do people choose their…

What are 2 ethical concerns associated with the commercialization of polygenic scores for diagnostics? Explain each issue briefly, and what can be done to mitigate it.

Which of the following would NOT be characteristic of a single-source non-compromised STR profile? Group of answer choices A.   No more than two (2) allelic peaks at any locus. B.   Well-balanced heterozygote peaks. C.   Sharply pointed peaks with even spectral distribution D.   Well-defined smooth peaks with a bell-shaped distribution.