The figure below shows a ribosome in the process of translating an mRNA with the sequence: 5’…AUGCCGUAUGCUCUUUAA…3’ a. The right side shows the ribosome with an empty A site aligned with the codon 5’UAU 3’. The next tRNA to occupy the A site on the ribosome will have what anti-codon sequence ( label 5’ and 3’)? Keep in mind the wobble pairing rules and make sure your answer is consistent with the genetic code. Explain your answer.  b.  Suppose, just as the ribosome started translating the mRNA, the cell suddenly lost all of its alanine tRNAs. Using the figure above as a guide, draw and label the state the ribosome would arrest in.

Anatomy & Physiology
1st Edition
ISBN:9781938168130
Author:Kelly A. Young, James A. Wise, Peter DeSaix, Dean H. Kruse, Brandon Poe, Eddie Johnson, Jody E. Johnson, Oksana Korol, J. Gordon Betts, Mark Womble
Publisher:Kelly A. Young, James A. Wise, Peter DeSaix, Dean H. Kruse, Brandon Poe, Eddie Johnson, Jody E. Johnson, Oksana Korol, J. Gordon Betts, Mark Womble
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The figure below shows a ribosome in the process of translating an mRNA with the sequence: 5’…AUGCCGUAUGCUCUUUAA…3’

a. The right side shows the ribosome with an empty A site aligned with the codon 5’UAU 3’. The next tRNA to occupy the A site on the ribosome will have what anti-codon sequence ( label 5’ and 3’)? Keep in mind the wobble pairing rules and make sure your answer is consistent with the genetic code. Explain your answer. 

b.  Suppose, just as the ribosome started translating the mRNA, the cell suddenly lost all of its alanine tRNAs. Using the figure above as a guide, draw and label the state the ribosome would arrest in.

 

 

Elongation
5
3
5
3
5
3
P site
A site
Met
Anticodon
tet
Amino
Incoming
tRNA
terminus
e 2001 Sinauer Associates, Inc.
Transcribed Image Text:Elongation 5 3 5 3 5 3 P site A site Met Anticodon tet Amino Incoming tRNA terminus e 2001 Sinauer Associates, Inc.
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