Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN: 9780134580999
Author: Elaine N. Marieb, Katja N. Hoehn
Publisher: PEARSON
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The best strategy for treating a specific type of human tumor can depend on identifying the
type of cell that became cancerous to give rise to the tumor. For some tumors that have
colonized a distant location (metastasized), identifying the parental cell type can be difficult.
Because the type of IF protein expressed is cell-type-specific, using monoclonal antibodies that
react with only one type of IF protein can help in this identification. What IF proteins would you
produce monoclonal antibodies against to identify (a) a sarcoma of muscle cell origin, (b) an
epithelial cell carcinoma, and (c) an astrocytoma (glial cell tumor)?
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Transcribed Image Text:The best strategy for treating a specific type of human tumor can depend on identifying the type of cell that became cancerous to give rise to the tumor. For some tumors that have colonized a distant location (metastasized), identifying the parental cell type can be difficult. Because the type of IF protein expressed is cell-type-specific, using monoclonal antibodies that react with only one type of IF protein can help in this identification. What IF proteins would you produce monoclonal antibodies against to identify (a) a sarcoma of muscle cell origin, (b) an epithelial cell carcinoma, and (c) an astrocytoma (glial cell tumor)?
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