The best strategy for treating a specific type of human tumor can depend on identifying the type of cell that became cancerous to give rise to the tumor. For some tumors that have colonized a distant location (metastasized), identifying the parental cell type can be difficult. Because the type of IF protein expressed is cell-type-specific, using monoclonal antibodies that react with only one type of IF protein can help in this identification. What IF proteins would you produce monoclonal antibodies against to identify (a) a sarcoma of muscle cell origin, (b) an epithelial cell carcinoma, and (c) an astrocytoma (glial cell tumor)?

Q: directly to DNA and plays a critical role in determining whether the DNA will be repaired or the…

A: p53 Mutations are a Frequent Event in Cancer:--The evolution in a normal cell producing cancerous…

Q: D. What is the best term for a normal INK gene? (tumor suppressor) (inactive tumor suppressor)…

A: Tumor-suppressor genes are those genes which do not allow the cell to grow rapidly and in an…

Q: Cancer stem cells (CSCs) are cancer cells (found within tumors or hematological cancers) that…

A: Stem cells are defined by their ability to self-renew as well as differentiate into a variety of…

Q: Describe the general process of cell signalling pathways: what events take place for a signal to…

A: * mainly there are Three Stages of Cell Signaling . The first one is reception and here the signal…

Q: Which of the following statements are correct about cancer drug resistance (select all that apply)?

A: Cancer drug resistance is the acquired after treatment effects that many of the Cancer Patients…

Q: Platelet-derived growth factor (PDGF) is, as its name suggests, stored in and secreted by platelets.…

A: PDGF is naturally synthesized and stored by the body. Its primary role is to encourage the growth…

Q: Why is it important to model cancer through the generation of induced pluripotent stem cells ?…

A: Induced pluripotent stem cells (iPS) is a type of stem cell(pluripotent) in nature that is derived…

Q: Discuss the behaviors of cancer cells that maydifferentiate their growth from that of normal cells.

A: Cell growth or cell proliferation is a process by which the cells grow in number through multiple…

Q: List and define the two general types of tumor.

A: KEY WORDS :- Tumor - It is a cancerous mass or lump caused by abnormal division of cells. It can be…

Q: When the doctor does blood work on Bob at this point, what blood cells do you expect to be at lower…

A: Red blood cells/ Erythrocytes will be lower than the normal count.

Q: hallmarks of tumor cells

A: Introduction:-The hallmarks constitutes an organizing principle for rationalising the complexities…

Q: None

A: QQ Plots for NormalityThe QQ plots below check the normality assumption for tumor and normal…

Q: Cellular reprogramming and induced pluripotent stem cells have allowed scientists to model various…

A: Pluripotent stem cells are the cells that can be developed into any cell in the body. The stem cells…

Q: Download and read the attached review article…

A: Some cancer patients would only need one operation. Many patients, on the other hand, undergo a…

Q: Name Pancytokeratin (CK) Vimentin Photomicrographs of marker expression Task Mark on the picture: 1-…

A: Immunohistochemistry- Immunohistochemistry is simply the biological application of immunostaining…

Q: ene therapy approaches have been studied for cancer gene therapy. These approaches include? (select…

A: Cancer Cancer is a serious disease marked by an abnormal and uncontrolled cell division of cells…

Q: RG, a 6-year-old child, has been diagnosed with Acute Lymphoblastic Leukemia (ALL). The standard…

A: Multiple subparts are asked. I will answer 1st 3 subparts in the question, as per guidelines. Given…

Q: What are the normal functions of the BRCA1 tumor suppressor gene?

A: The BRCA1 gene codes for the protein that causes breast cancer type 1. BRCA1 is a human tumour…

Q: Given the following scenario, indicate if this will ‘promote’ or ‘prevent’ cancer development: An…

A: Bcl-2, or B-cell lymphoma 2, is a protein that plays a crucial role in regulating apoptosis…

Q: name any two methods that can possibly cure cancer .

A: Cancers are one of the most common cause of death in the modern world.  Currently cancer treatment…

Q: For many years, targeted therapies for cancer treatment continue to be developed, however more and…

A: Targeted therapy is a type of cancer treatment that uses drugs designed to "target" cancer cells…

Q: 1. Based on your figure of the cells under the microscope in the picture (10x magnification) , list…

A: The extracellular matrix (ECM) is an intricate network consisting of extracellular macromolecules…

Q: In a cancer research lab,normal cells have specific biomarker AAP1 while cancer cell display SSR1…

A: Cancer is the uncontrolled growth of abnormal cells in a body. Cancer arises as a result of…

Q: Characterize the differences between tumor cells and normal cells in terms of the following…

A: A. The normal cell shows contact inhibition that means when two cells get contact then the growth…

Q: Name the six fundamental properties of malignant tumours. Which of these properties are amenable to…

A: Malignant cells grow uncontrollably, invading nearby tissues and spreading to other parts of the…

Q: Which is a.) Reduction of cancer risks b.) Correction of cancer genes or c.) Destruction of cancer…

A: Cancer is a disease caused by the uncontrolled proliferation of cells due to the defects in the cell…

Q: Tumor growth rate is dependent on which of the following factors? A. Quantity of actively dividing…

A: Tumor growth is the growth of the cancerous cells in the body.

Q: Explain why metastasis can lead to multiplesecondary tumors in different sites.

A: When there is some mutation that occurs in the DNA of any cell that leads to abnormal and…

Q: Which of the following statements are correct about tumors and metastasis (select all that apply)?…

A: Tumor is an abnormal mass of cells which grow and divide more than their requirement or they do not…

Q: You have two patients with pancreatic cancer. Patient 1 has a KRAS oncogenic mutation; a myc…

A: Answer a : - CBP-93872 is the most effective in patients having loss of function mutation for tumour…

Q: In a patient diagnosed with a Squamous cell carcinoma that exhibits high Base Excision Repair…

A: PARP1 inhibitors are a type of targeted cancer therapy that exploit the concept of synthetic…

Q: Describe error prone polymerases and the process of translesion synthesis (TLS). In regards to tumor…

A: Translesion synthesis (TLS) is a method of overcoming stopped replication in which particular…

Q: Looking at Figure 1, what did Romansik et al. (2007) find regarding the relationship between the…

A: The mitotic index is a measure of the number of cells in a tissue sample that are undergoing cell…

Q: Why is the p53-meditated apoptosis pathway, and the GSK3 signaling pathway important for cancer…

A: p53 is a critical tumour suppressor that is mutated in ~50% of human cancers. Inunstressed cells p53…

Q: dentify two genetic mechanisms whereby proto-oncogenes can become overexpressed.Select the two…

A: Activation of Proto-oncogenes. Proto-oncogenes are normal cell proliferating genes that encode cell…

Q: Which of the following are charcteristics you would expect of a circulating tumor cell that has…

A: An epithelial cell that has undergone transition into a mesenchymal cell, helps in both…

Q: trigger

A: The process of programmed cell death is called apoptosis. Apoptosis aids in the prevention of…

Q: Which of the following would be considered a commonly acquired characteristic of cancer cells?…

A: Cancer cells exhibit a range of distinct characteristics. These characteristics, often referred to…

Q: The growth fraction of the cancer types A 8, C, and D are 23%, 45, 56%, and 78%, respectively. Which…

A: Fast-growing cells would be affected the most and slow-growing cells would be least disturbed. In…

Q: In a Cervical Cancer screening program, 500 asymptomatic women were examined using the Pap smear…

A: Cervical Cancer screening program is a screening test for testing women who are at risk of cervical…

Q: umor markers

A: Tumor is an abnormal mass of tissue that forms after unusual cell growth and division. Tumors can be…

Q: Over time, cancer cells are known to produce weakly antigenic variants of cell surface proteins.…

A: Tumour antigens are those that are displayed on the surface of tumour cells by MHC class I or II…

Genomic studies

Genomic studies (genomics) is the study of the whole genome of an organism. Using bioinformatics and high-performance computing, genomic researchers examined massive amounts of deoxyribonucleic acid (DNA)-sequence data to discover variations or mutations that affect drug response, health, or disease. Genomics is a much younger discipline than genetics, having only emerged in the last few decades as a result of technological advancements in DNA sequencing and computational biology.