Why are PARP inhibitors effective in killing tumor cells with BRCA-deficiency but not Rb deficiency? O PARP is a tumor suppressor that drives Rb-deficient tumor cells PARP inhibitors are effective in killing both BRCA-deficient and Rb-deficient tumor cells because they perform a similar function O PARP inhibitors are effective in killing cells that bypass cell cycle checkpoints O PARP inhibitors are effective in killing cells without redundant DNA repair mechanisms O PARP is an oncogene that drives BRCA-deficient tumor cells

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Environmental health and hazards

An organism's environment is the environment in which it lives and has an impact on its well-being. The World Health Organization (WHO) defines environmental health as "those aspects of public health, such as quality of life, that are influenced by physical, chemical, biological, social, and psychosocial components in the environment." Environmental health is concerned with both natural and man-made settings in order to enhance public health. Environmental science, occupational medicine, toxicology, and epidemiology are the key subdisciplines of environmental health.