Why are PARP inhibitors effective in killing tumor cells with BRCA-deficiency but not Rb deficiency? O PARP is a tumor suppressor that drives Rb-deficient tumor cells PARP inhibitors are effective in killing both BRCA-deficient and Rb-deficient tumor cells because they perform a similar function O PARP inhibitors are effective in killing cells that bypass cell cycle checkpoints O PARP inhibitors are effective in killing cells without redundant DNA repair mechanisms O PARP is an oncogene that drives BRCA-deficient tumor cells

17 STRE

Can someone help me plz

Mary O'Keefe calls the Inner City Health Care office in a panic. Gwen Carr, CMA (AAMA), answers the telephone. Mary: "Oh my God, help me. I need Dr. King." Gwen: "This is Ellen Armstrong, Who is this calling? What is the situation?" Mary: "It's my haby, oh God, get Dr. King." Gwen: "Dr. King is unavailable, but we can help you. Now, tell me your name." Mary: "It's Mary O'Keefe. Help me, I think my baby is dead." Gwen: "Are you at home?" Mary: "Yes" Gwen: "Ok. Try to calm down. Speak slowly and tell me what's happened." Mary: "My son Chris pried the plug off an outlet and he's electrocuted himself!" Mary cries. "He's just lying there. I'm so scared, if I touch him, will I electrocute myself? Oh my God, my baby, my baby. What should I do?" Gwen, who has been writing down the details on a piece of paper, motions to Joe Guerrero, another CMA (AAMA) in the office, and hands him her notes. Joe immediately accesses the O'Keefe address from the patient database and uses…