The amino acid glycine is often used as the main ingredient of a buffer in biochemical experiments. The amino group of glycine, which has a pKa of 9.6, can exist either in the protonated form. (a) In what pH range can glycine be used as an effective buffer due to its amino group? (b) When 99% of the glycine is in its protonated form, what is the numerical relation between the pH of the solution and the pKa of the amino group?

Biochemistry
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Chapter1: Biochemistry: An Evolving Science
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The amino acid glycine is often used as the main ingredient of a buffer
in biochemical experiments. The amino group of glycine, which has a
pKa of 9.6, can exist either in the protonated form.


(a) In what pH range can glycine be used as an effective buffer due to its
amino group?
(b) When 99% of the glycine is in its protonated form, what is the numerical relation between the pH of the solution and the pKa of the amino group?

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