QUESTION distone modifying enzymes can be over- or under-expressed in a variety of human diseases and cancers. How would overexpression of histone methyltransferases affect transcription throughout the genome? O transcription could be increased or decreased depending on which amino acids in histone proteins were modified by this enzyme O transcription would be increased O transcription would be decreased O transcription would not be affected

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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QUESTION 6
Histone modifying enzymes can be over- or under-expressed in a variety of human diseases and cancers. How would overexpression of histone methyltransferases affect transcription throughout the genome?
O transcription could be increased or decreased depending on which amino acids in histone proteins were modified by this enzyme
O transcription would be increased
O transcription would be decreased
O transcription would not be affected
QUESTION 7
Eukaryotic genomes contain multiple origins of replication, whereas the E. coli genome contains a single origin of replication. Pick the reason(s) that eukaryotes need multiple replication origins from the list below.
O Eukaryotes have large genomes
O Eukaryotes have multiple chromosomes
O Eukaryotic chromosomes are linear
O Eukaryotic DNA is packaged in chromatin
O Eukaryotes use both leading-strand and lagging-strand DNA synthesis
O Eukaryotes use multiple DNA polymerases
QUESTION 8
Describe the role the branch point ribose 2'-OH plays in intron removal.
O A. forms a bond with the 5' phosphate of the intron to produce a lariat
O B. regulates alternative splicing of some RNAS
O C. forms a bond with the 3' hydroxyl group of the intron to produce a lariat
O D. catalyzes the removal of self-splicing introns
O E. recognized by snRNAs in the spliceosome by base-pair complementarity
Transcribed Image Text:QUESTION 6 Histone modifying enzymes can be over- or under-expressed in a variety of human diseases and cancers. How would overexpression of histone methyltransferases affect transcription throughout the genome? O transcription could be increased or decreased depending on which amino acids in histone proteins were modified by this enzyme O transcription would be increased O transcription would be decreased O transcription would not be affected QUESTION 7 Eukaryotic genomes contain multiple origins of replication, whereas the E. coli genome contains a single origin of replication. Pick the reason(s) that eukaryotes need multiple replication origins from the list below. O Eukaryotes have large genomes O Eukaryotes have multiple chromosomes O Eukaryotic chromosomes are linear O Eukaryotic DNA is packaged in chromatin O Eukaryotes use both leading-strand and lagging-strand DNA synthesis O Eukaryotes use multiple DNA polymerases QUESTION 8 Describe the role the branch point ribose 2'-OH plays in intron removal. O A. forms a bond with the 5' phosphate of the intron to produce a lariat O B. regulates alternative splicing of some RNAS O C. forms a bond with the 3' hydroxyl group of the intron to produce a lariat O D. catalyzes the removal of self-splicing introns O E. recognized by snRNAs in the spliceosome by base-pair complementarity
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