QUESTION 13 You have isolated a nonsense mutation caused by a base substitution. This mutation is a null allele. You then use this mutant to select for second mutations that suppress the null phenotype back to a more wild-type phenotype. In theory, which of of the following types of second mutations are possible? O A reverse mutation of the nonsense mutation O A mutation in the anticodon of a tRNA gene O A precise deletion of the codon containing the nonsense mutation

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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QUESTION 13
You have isolated a nonsense mutation caused by a base substitution. This mutation is a null allele. You then use this mutant to select for second mutations that suppress the null
phenotype back to a more wild-type phenotype. In theory, which of of the following types of second mutations are possible?
A reverse mutation of the nonsense mutation
A mutation in the anticodon of a tRNA gene
precise deletion of the codon containing the nonsense mutation
Transcribed Image Text:QUESTION 13 You have isolated a nonsense mutation caused by a base substitution. This mutation is a null allele. You then use this mutant to select for second mutations that suppress the null phenotype back to a more wild-type phenotype. In theory, which of of the following types of second mutations are possible? A reverse mutation of the nonsense mutation A mutation in the anticodon of a tRNA gene precise deletion of the codon containing the nonsense mutation
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