Question 4.6 Homework • Unanswered Regarding the antigen receptor repertoires of lymphocyte populations, which of the following Venn diagrams best illustrates the relationship between the 'universal (or open) repertoire' of immature lymphocytes and the 'functional repertoire' of mature lymphocytes: A B Open Functional Open Functional Functional Open Select an answer and submit. For keyboard navigation, use the up/down arrow keys to select an answer. Diagram A a Diagram B Diagram C
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- Need help Explain the role of dendritic cells in determining T-cell effector subtype, including where these reactions take place. What is the relationship between dendritic cells and/or effector T-cell subsets and antibody isotype?Which statements are true? Explain why or why not.1 T cells whose receptors strongly bind a self-pep-tide–MHC complex are killed off in peripheral lymphoidorgans when they encounter the self peptide on an anti-gen-presenting dendritic cell. 2 To guarantee that the antigen-presenting cells inthe thymus will display a complete repertoire of self pep-tides to allow elimination of self-reactive T cells, the thy-mus recruits dendritic cells from all over the body. 3 The antibody diversity created by the combinato-rial joining of V, D, and J segments by V(D)J recombinationpales in comparison to the enormous diversity created bythe random gain and loss of nucleotides at V, D, and J join-ing sites.Question:- Biology Describe the cellular branch of adaptive immunity and name its key effector cells. Describe how the two types of MHCs present antigens and summarize how MHCs impact transplant rejection. Explain the two-signal mechanism of T cell activation and discuss the factors that affect subclass differentiation
- Question:- Which of the following statements concerning T cell development is correct? A. Progenitor T cells that enter the thymus from the bone marrow express CD4 or CD8 B. Interaction with thymic non-lymphoid cells is critical C. Maturation in the thymus requires the presence of foreign antigen D. MHC II molecules are not involved in positive selectionQuestion 6 Save Answer What immune response would a mild breakthrough infection by the Omicron-variant SARS-CoV- 2 most likely cause in a fully COVID vaccinated person? a. Only T-cells will be stimulated. b. The infection will use up all the residual anti-COVID antibodies. c. With the breakthrough infection, the COVID-stimulated plasma cells will release interleukins that will cause the natural killer cells to forget to alert the memory B cells to activate the complement system, and then the nose gets runny. d. The infection will give an additional increase in the overall immune response.Comprehensively explain why the D antigen is the most immunogenic of all the blood group proteins. Can a person with a weak D phenotype safely receive D- positive blood? Why? Why not? (If not, what type (in terms of Rh) should this individual receive? How should weak D blood units be labeled? Can a D-negative patient safely receive weak D blood? Why? Why not? Can a person with a partial D phenotype safely receive D- positive blood? Why? Why not? (If not, what type (in terms of Rh) should this individual receive? Is it possible to transfuse Rh- positive blood to Rh-negative recipients? Name several conditions that should be met when transfusing Rh- positive blood to Rh- negative recipients. Which individuals (priority list) should receive Rh- negative blood? Explain.
- Question:- Place these in the order in which they occur in the immune system. What order do these events relating to effector responses occur in? Activated B cells leave lymph nodes and move into bloodstream Activated B and T cells exit the blood stream at the site of infection Activated T cells leave lymph nodes and move into bloodstream Activated Tcytotoxic cells look for and kill infected self cells Antibodies bind directly to non-self microbes Antibodies help improve phagocytosis (‘opsonization’) Antibodies leak out of bloodstream at site of infection Antibodies secreted in lymph node travel through bloodstream Memory B and T cells patrol around the body looking to be activated by the same microbial substances that activated them in the first place.Question 5 Save Answer Several months after the initial vaccination schedule to achieve COVID immunity, the protection against COVID diminishes, and "boosters" are recommended to re-establish full immune protection. What is the part of the immune response that naturally wanes or diminishes during that time so that boosters are needed? a. Levels of circulating antibodies such as lgG decrease because of their usual half-life in the blood. O b. The antigen processing dendrites stop working because they get tired of doing all that hard work and not getting proper recognition and credit. c. Natural killer cells lose their ability to recognize and kill virus-infected cells. d. The memory B-cells lose the ability to remember the SARS-CoV-2 antigens.O https://learn.humber.ca/ultra/courses/_182213_1/cl/outline * Question Completion Status: QUESTION 15 A karyotype (a chromosome display) would be unable to determine O sex O Down syndrome O Turner syndrome O eye colour QUESTION 16 Antibodies are shaped like the letter B are shaped like the letter B are generalists in that any antibody can bind to any antigen assist in destroying particular antigens Oare produced by T cells e all answers.
- Class I major histocompatibility complex molecules are found on O all anucleated cells. O antigen-presenting O all nucleated O None of the choices are correct. QUESTION 67 Important characteristics of antimicrobic drugs include O readily delivered to the site of infection. O high toxicity against microbial cells. O remains active in body tissues and fluids. do not cause serious side effects in humans. O All of these choices are correct. QUESTION 68 Antibodies O can bind to an immunogen. O are part of the nonspecific immune response. O can target the immunogen for destruction. O both can bind to an immunogen and can target the immunogen for destruction. O both can bind to an immunogen and are part of the nonspecific immune response.and eu Workbook Exercise 10: Blood Examine a slide of blood looking for a field where the cells are not too densely or sparsely spread, and give appropriate response to the following. dide of blood cells is refered to as a smear or a film, why? . Lymphoe 2 on of very Give the names of three mixtures of dyes used for routine staining of blood films. ()- by a thin rim aucleus. La (1). g nucleus w circular structures with pale as the slide appear 3. Why do erythrocytes on centres?. ne slide de od so you 5. What does the lack of mitochondria and a relatively long life span suggest about the metabolism of an erythrocyte? . ghbours 4. What accounts for the acidophilia of erythrocytes? pulations"Gamma-delta' T cells differ from 'alpha-beta' T cells by all of the following except O alpha-beta cells are more commonly found in skin and other tissues, while gamma-delta cells are primarily in lymph nodes. gamma-delta cells undergo more hypermutation for their receptor genes. gamma-delta cells respond more with non-peptide antigens, especially phospholipids. O production of an effector response occurs more rapidly in alpha-beta T cells.