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- Class I major histocompatibility complex molecules are found on O all anucleated cells. O antigen-presenting O all nucleated O None of the choices are correct. QUESTION 67 Important characteristics of antimicrobic drugs include O readily delivered to the site of infection. O high toxicity against microbial cells. O remains active in body tissues and fluids. do not cause serious side effects in humans. O All of these choices are correct. QUESTION 68 Antibodies O can bind to an immunogen. O are part of the nonspecific immune response. O can target the immunogen for destruction. O both can bind to an immunogen and can target the immunogen for destruction. O both can bind to an immunogen and are part of the nonspecific immune response.Which of the flollowing reasons DOES NOT account for the barrier protective effect of IL-22? Students, this question was not on your reading, but you should be able to answer correctly. O stimulates cell survival and prliferation O stimulates synthesis of antimicrobilas like defensins etc prevents neuro-immune cross tqalk takes effect on stromal and epithelial cellsHelper T cells can be activated by macrophages(which engulf everything indiscriminately) or by B cells (which only engulf antigens that stick to their receptors). A. What properties so macrophages and B cells have ibn common that allows them both to activate T cells? B. It has been suggested that macrophages probably do most to fhte T cell activating in the primary response but B cells do most of it in the secondary response. Why does this make sense?
- Complement activation is a cascade reaction, with each component sequentiallyacting on others, in a similar way to the blood-clotting system. Discuss the effectsthat occur when peptides are generated from the activation by either the classicalor the alternative pathway. This is an immunology questionAll are direct effects of histamines and leukotrienes on capillaries except Oa chemotaxin factor Ob vasodilation: Oc allew for diapedesh (extravasation) Od. lncroase blood Row QUESTION 2 In tuberculosis, these pockets of chronically infected tissue are formed when phagocytes are unsuccessful in removing a pathogen. Oa phagolysosomes Ob. granulomas Oe diapedésis Od. chemotaxis QUESTION 3 Granuloctye phagocyte, most abundant leukocyte, raleases NETS to kiil nearty pathogens On Ensinophil O b. Basophia O. Dendritic cel Od. Neutrophilthat causes the rapid reproduction of a specific ( Select] [ Select ] Antigenic cell B cell I cell Macrophage Eosinophil Vaccines work by stimulating a(n) [Select ] that produces an antibody that is specific for the antigen in the vaccine. This creates a pool of memory cells that will be available if the person is ever infect nicrobe.
- When the BCR (B Cell Receptor) & complement receptor are brought together, or "cross-linked", the signal sent by the BCR to the cell nucleus is greatly O muted O mixed O amplified O reduced79 55. One week after a cadaveric kidney allograft, a 45-year-old man develops a fever. He has a 24-hour urine output of 100 mL and a serum creatinine concentration of 3.5 these cells, IL-2 receptor is a useful marker of which of the following cellular processes? mg/dL. A renal biopsy specimen shows an infiltrate of CD3+ T lymphocytes that are positive for interleukin-2 (IL-2) receptor (CD25) on immunocytochemical testing. For A) Activation B) Differentiation C) Ontogenic development OD) SenescenceWhich of the following best describes the function of IgA antibodies? O Allergy response O Defense against pathogens at mucosal surfaces by neutralizing them and preventing their attachment to host cells Activation of complement system to destroy bacteria and viruses Killing infected cells by recognizing and attacking their surface antigens Which of the following statements about cytotoxic T cells and MHC is true? O Cytotoxic T cells recognize antigens presented by MHC class I molecules on the surface of all cells in the body. O MHC class I molecules are only found on antigen-presenting cells, such as dendritic cells and macrophages and not on cytotoxic T cells O MHC class Il molecules are only found on infected cells, which present antigens to cytotoxic T cells. O Cytotoxic T cells recognize antigens presented by MHC class II molecules on the surface of all cells in the body.
- Which of the following is a TRUE statement regarding the effect of high doses of corticosteroids, such as dexamethasone, on the imnune system? O None of the statements apply Functions to inhibit IgG secretion from autoimmune B cells O Functions to specifically inhibit cyclooxygenase-2 (COX-2) to decrease pain and inflammation Functions to inhibit enzyme phospholipase A2, which causes lethal disruption of WBC function (WBC death) OFunctions to inhibit enzyme phospholipase A2, which decreases cyclooxygenase- 2 (COX-2) levelsQUESTION 1 An epitope associates with which part of an antigen receptor? O The heavy-chain constant regions only O The light-chain constant regions only O The tail Variable regions of a heavy chain and light chain combinedConcerning structure and function of antibodies, which of the following statements is INCORRECT: a. Each antibody can recognise thousands of antigens b. Antibodies can activate complement cascade c. An antibody usually has a complement binding site, a macrophage binding site, and anantigen binding site d. Antibodies can act as opsonins e. Antibodies can neutralise toxins Which of the following is NOT a component of the innate immune defence: a. Mucous membranes trapping foreign invaders b. Complement proteins stimulating phagocytosis c. Phagocytes killing invaders d. Low pH in stomach preventing bacterial growth e. Vaccines preventing infection by inducing memory