Which statements are true? Explain why or why not.1 T cells whose receptors strongly bind a self-pep-tide–MHC complex are killed off in peripheral lymphoidorgans when they encounter the self peptide on an anti-gen-presenting dendritic cell. 2 To guarantee that the antigen-presenting cells inthe thymus will display a complete repertoire of self pep-tides to allow elimination of self-reactive T cells, the thy-mus recruits dendritic cells from all over the body. 3 The antibody diversity created by the combinato-rial joining of V, D, and J segments by V(D)J recombinationpales in comparison to the enormous diversity created bythe random gain and loss of nucleotides at V, D, and J join-ing sites.
Which statements are true? Explain why or why not.1 T cells whose receptors strongly bind a self-pep-tide–MHC complex are killed off in peripheral lymphoidorgans when they encounter the self peptide on an anti-gen-presenting dendritic cell. 2 To guarantee that the antigen-presenting cells inthe thymus will display a complete repertoire of self pep-tides to allow elimination of self-reactive T cells, the thy-mus recruits dendritic cells from all over the body. 3 The antibody diversity created by the combinato-rial joining of V, D, and J segments by V(D)J recombinationpales in comparison to the enormous diversity created bythe random gain and loss of nucleotides at V, D, and J join-ing sites.
Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN:9781305251052
Author:Michael Cummings
Publisher:Michael Cummings
Chapter17: Genes And The Immune System
Section: Chapter Questions
Problem 21QP
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Question
Which statements are true? Explain why or why not.
1 T cells whose receptors strongly bind a self-pep-
tide–MHC complex are killed off in peripheral lymphoid
organs when they encounter the self peptide on an anti-
gen-presenting dendritic cell.
2 To guarantee that the antigen-presenting cells in
the thymus will display a complete repertoire of self pep-
tides to allow elimination of self-reactive T cells, the thy-
mus recruits dendritic cells from all over the body.
3 The antibody diversity created by the combinato-
rial joining of V, D, and J segments by V(D)J recombination
pales in comparison to the enormous diversity created by
the random gain and loss of
ing sites.
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